Redox dysfunctions and neuro-oxidative stress play a major role in the pathophysiology and
progression of Parkinson's disease (PD). Glutathione (GSH) and the reduced/oxidized …

Glucose is the main energy substrate for the brain. There is now extensive evidence
indicating that the metabolic profile of neural cells with regard to glucose utilization and …

Oxidative stress (OS) disrupts the chemical integrity of macromolecules and increases the
risk of neurodegenerative diseases. Fisetin is a flavonoid that exhibits potent antioxidant …

The role of glutathione in autism spectrum disorder (ASD) is emerging as a major topic, due
to its role in the maintenance of the intracellular redox balance. Several studies have …

Alzheimer's disease (AD) accounts for two-thirds of all dementia cases, affecting 50 million
people worldwide. Only four of the more than 100 AD drugs developed thus far have …

Amyloid beta (Aβ) accumulates within neurons in the brains of early stage Alzheimer's
disease (AD) patients. However, the mechanism underlying its toxicity remains unclear …

Ferroptosis is a novel regulated cell death characterized by metabolic disorders and iron-
dependent oxidative destruction of the lipid bilayer. It is primarily caused by the imbalance of …

Astrocytes have a pivotal role in brain as partners of neurons in homeostatic and metabolic
processes. Astrocytes also protect other types of brain cells against the toxicity of reactive …

One of the hallmarks of cancer is the ability to generate and withstand unusual levels of
oxidative stress. In part, this property of tumor cells is conferred by elevation of the cellular …

The present paper is aimed at providing an overview of the recent advances in the
electrochemical sensing of glutathione (GSH), an important electrochemically and …