The notion that stress and cancer are interlinked has dominated lay discourse for decades.
More recent animal studies indicate that stress can substantially facilitate cancer …

Glucocorticoids have been used in clinical oncology for over half a century. The clinical
applications of glucocorticoids in oncology are mainly dependent on their pro-apoptotic …

Diversity within or between tumours and metastases (known as intra-patient tumour
heterogeneity) that develops during disease progression is a serious hurdle for therapy …

Triple-negative breast cancer (TNBC) has the lowest 5-year survival rate of invasive breast
carcinomas, and currently there are no approved targeted therapies for this aggressive form …

Breast cancer is the most common cancer diagnosed in women. It is associated with multiple
symptoms in both patients and caregivers, such as stress, anxiety, depression, sleep …

The Hippo pathway is an oncosuppressor signalling cascade that plays a major role in the
control of cell growth, tissue homoeostasis and organ size. Dysregulation of the Hippo …

Chronic stress results in disturbances of body hormones through the neuroendocrine
system. Cancer patients often experience recurrent anxiety and restlessness during disease …

Breast cancer (BC) is still characterized by high morbidity and mortality. A specific BC
subtype named triple negative BC (TNBC) lacks estrogen and progesterone receptors (ER …

The Hippo pathway plays a critical role in cell growth and tumorigenesis. The activity of TEA
domain transcription factor 4 (TEAD4) determines the output of Hippo signaling; however …

Breast cancer (BC) remains the primary cause of death from cancer among women
worldwide. Cholesterol-5, 6-epoxide (5, 6-EC) metabolism is deregulated in BC but the …