Cancer is one of the world's biggest healthcare burdens and despite the current
advancements made in treatment plans, the outcomes for oncology patients have yet to …

Hollow‐structured nanomaterials (HSNMs) have attracted increased interest in biomedical
fields, owing to their excellent potential as drug delivery systems (DDSs) for clinical …

As a terpenoids natural product isolated from the plant Thunder God Vine, Celastrol is
widely studied for its pharmacological activities, including anti-tumor activities. The clinical …

Natural chemical compounds have been widely investigated for their programmed necrosis
causing characteristics. One of the conventional methods for screening such compounds is …

Metabolic diseases are becoming increasingly common in modern society. Therefore, it is
essential to develop effective drugs or new treatments for metabolic diseases. As an active …

Exosomes are small phospholipid bilayer vesicles that are naturally produced by all living
cells, both prokaryotes and eukaryotes. The exosomes due to their unique size, reduced …

Immunotherapy treatments harnessing the immune system herald a new era of personalized
medicine, offering considerable benefits for cancer patients. Over the past years, tumor …

Background Pancreatic cancer is one of the most serious and lethal human cancers with a
snowballing incidence around the world. The natural product celastrol has also been widely …

Reactive oxygen species (ROS) are metabolic byproducts that regulate various cellular
processes. However, at high levels, ROS induce oxidative stress, which in turn can trigger …

Introduction Breast cancer (BC) accounts for the majority of cancers among the female
population. Anomalous activation of various signaling pathways has become an issue of …