Biliary Atresia–emerging diagnostic and therapy opportunities

U Lendahl, VCH Lui, PHY Chung, PKH Tam - EBioMedicine, 2021 - thelancet.com
Biliary Atresia is a devastating pediatric cholangiopathy affecting the bile ducts of the liver. In
this review, we describe recent progress in the understanding of liver development with a …

Systematic review: the quality of life of patients with biliary atresia

M Le, K Reinshagen, C Tomuschat - Journal of Pediatric Surgery, 2022 - Elsevier
Background The quality of life of patients with Biliary Atresia (BA) have not been
systematically examined. The goal of this meta-analysis is to determine patients' …

Surgical and medical aspects of the initial treatment of biliary atresia: Position paper

M Davenport, O Madadi-Sanjani, C Chardot… - Journal of Clinical …, 2022 - mdpi.com
Biliary atresia, a fibro-obliterative disease of the newborn, is usually initially treated by Kasai
portoenterostomy, although there are many variations in technique and different options for …

Spectral analysis with highly collimated mini-LEDs as light sources for quantitative detection of direct bilirubin

ZT Ye, SF Tseng, SX Tsou, CW Tsai - Discover Nano, 2024 - Springer
Because the human eye cannot visually detect the results of direct bilirubin test papers
accurately and quantitatively, this study proposes four different highly collimated mini light …

Kasai portoenterostomy delays: is a HIDA scan worth the wait?

YZ Lim, U Chaudhary, Y Issioui, N Corbitt - Journal of Pediatric Surgery, 2023 - Elsevier
Abstract Background Biliary Atresia (BA), an obstructive cholangiopathy, is the most
common cause of end-stage liver disease and liver transplantation in children. Timely …

Impact of gallbladder hypoplasia on hilar hepatic ducts in biliary atresia

N Miyazaki, S Takami, M Uemura, H Oiki… - Communications …, 2024 - nature.com
Background Biliary atresia (BA) is an intractable disease of unknown cause that develops in
the neonatal period. It causes jaundice and liver damage due to the destruction of …

Biliary atresia-specific deciduous pulp stem cells feature biliary deficiency

S Sonoda, K Yoshimaru, H Yamaza… - Stem cell research & …, 2021 - Springer
Background Biliary atresia (BA) is a severe hepatobiliary disease in infants that ultimately
results in hepatic failure; however, its pathological mechanism is poorly elucidated. Current …

Feasibility and outcomes of transjugular intrahepatic portosystemic shunts in infants

JJ Martínez-Rodrigo, A Boukhoubza, DP Enguix… - Pediatric …, 2023 - Springer
Background Experience with transjugular intrahepatic portosystemic shunts (TIPS) in the
pediatric population, especially in infants, is limited. Objective To evaluate the feasibility …

Combination of Pirfenidone and Andrographolide Ameliorates Hepatic Stellate Cell Activation and Liver Fibrosis by Mediating TGF‐β/Smad Signaling Pathway

G Xu, T Ma, C Zhou, F Zhao, K Peng… - Analytical Cellular …, 2024 - Wiley Online Library
Background. Biliary atresia (BA) is a devastating congenital disease characterized by
inflammation and progressive liver fibrosis. Activation of hepatic stellate cells (HSCs) plays a …

Cost-effectiveness analysis of liver transplantation in biliary atresia according to the severity of end-stage liver disease

B Sihaklang, S Getsuwan, O Pattanaprateep… - BMC pediatrics, 2023 - Springer
Background Timing for liver transplantation (LT) in biliary atresia (BA) children with end-
stage liver disease (ESLD) is associated with all-cause mortality. The cut-off value of …