Candida parapsilosis: from genes to the bedside

R Tóth, J Nosek, HM Mora-Montes… - Clinical microbiology …, 2019 - Am Soc Microbiol
Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …

Candida albicans-Biology, molecular characterization, pathogenicity, and advances in diagnosis and control–An update

M Dadar, R Tiwari, K Karthik, S Chakraborty… - Microbial …, 2018 - Elsevier
Candida albicans is an emerging multidrug-resistant fungal pathogen representing an
important source of invasive disease in humans and generating high healthcare costs …

[HTML][HTML] Rapid proliferation due to better metabolic adaptation results in full virulence of a filament-deficient Candida albicans strain

C Dunker, M Polke, B Schulze-Richter… - Nature …, 2021 - nature.com
The ability of the fungal pathogen Candida albicans to undergo a yeast-to-hypha transition
is believed to be a key virulence factor, as filaments mediate tissue damage. Here, we show …

[HTML][HTML] A Putative Role of Candida albicans in Promoting Cancer Development: A Current State of Evidence and Proposed Mechanisms

J Talapko, T Meštrović, B Dmitrović, M Juzbašić… - Microorganisms, 2023 - mdpi.com
Candida albicans is a commensal fungal species that commonly colonizes the human body,
but it is also a pervasive opportunistic pathogen in patients with malignant diseases. A …

Regulatory mechanisms controlling morphology and pathogenesis in Candida albicans

D Kadosh - Current opinion in microbiology, 2019 - Elsevier
Highlights•There is a strong association between C. albicans morphology and virulence.•C.
albicans morphology control mechanisms may serve as important antifungal …

The evolution of posttranscriptional regulation

B Schaefke, W Sun, YS Li, L Fang… - Wiley Interdisciplinary …, 2018 - Wiley Online Library
" DNA makes RNA makes protein." After transcription, mRNAs undergo a series of
intertwining processes to be finally translated into functional proteins. The …

[HTML][HTML] A Re-Evaluation of the Relationship between Morphology and Pathogenicity in Candida Species

D Kadosh, V Mundodi - Journal of Fungi, 2020 - mdpi.com
Many pathogenic Candida species possess the ability to undergo a reversible
morphological transition from yeast to filamentous cells. In Candida albicans, the most …

[HTML][HTML] Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence

NN Liu, P Uppuluri, A Broggi, A Besold, K Ryman… - PLoS …, 2018 - journals.plos.org
Phosphate is an essential macronutrient required for cell growth and division. Pho84 is the
major high-affinity cell-surface phosphate importer of Saccharomyces cerevisiae and a …

[HTML][HTML] Lactobacillus rhamnosus Lcr35 as an effective treatment for preventing Candida albicans infection in the invertebrate model Caenorhabditis elegans: First …

C Poupet, T Saraoui, P Veisseire, M Bonnet… - PLoS …, 2019 - journals.plos.org
The increased recurrence of Candida albicans infections is associated with greater
resistance to antifungal drugs. This involves the establishment of alternative therapeutic …

Living together: The role of Candida albicans in the formation of polymicrobial biofilms in the oral cavity

M Rapala‐Kozik, M Surowiec, M Juszczak… - Yeast, 2023 - Wiley Online Library
The oral cavity of humans is colonized by diversity of microbial community, although
dominated by bacteria, it is also constituted by a low number of fungi, often represented by …