[HTML][HTML] Chronic low grade inflammation in pathogenesis of PCOS

E Rudnicka, K Suchta, M Grymowicz… - International journal of …, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is a one of the most common endocrine disorders, with a
prevalence rate of 5–10% in reproductive aged women. It's characterized by (1) chronic …

Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective

S Kumariya, V Ubba, RK Jha, JR Gayen - Autophagy, 2021 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a unification of endocrine and metabolic disorders and
has become immensely prevalent among women of fertile age. The prime organ affected in …

[HTML][HTML] Metabolic syndrome and PCOS: Pathogenesis and the role of metabolites

W Chen, Y Pang - Metabolites, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases among
women of reproductive age and is associated with many metabolic manifestations, such as …

[HTML][HTML] Reactive oxygen species and ovarian diseases: Antioxidant strategies

J Liang, Y Gao, Z Feng, B Zhang, Z Na, D Li - Redox Biology, 2023 - Elsevier
Reactive oxygen species (ROS) are mainly produced in mitochondria and are involved in
various physiological activities of the ovary through signaling and are critical for regulating …

[HTML][HTML] Oxidative stress and low-grade inflammation in polycystic ovary syndrome: controversies and new insights

A Mancini, C Bruno, E Vergani, C d'Abate… - International Journal of …, 2021 - mdpi.com
The pathophysiology of Polycystic Ovary Syndrome (PCOS) is quite complex and different
mechanisms could contribute to hyperandrogenism and anovulation, which are the main …

[HTML][HTML] Modulation of the inflammatory response in polycystic ovary syndrome (PCOS)—searching for epigenetic factors

D Szukiewicz, S Trojanowski, A Kociszewska… - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of
reproductive age. Despite its incidence, the syndrome is poorly understood and remains …

[HTML][HTML] Enhanced glycolysis in granulosa cells promotes the activation of primordial follicles through mTOR signaling

X Zhang, W Zhang, Z Wang, N Zheng, F Yuan… - Cell death & …, 2022 - nature.com
In mammals, nonrenewable primordial follicles are activated in an orderly manner to
maintain the longevity of reproductive life. Mammalian target of rapamycin (mTOR)-KIT …

[HTML][HTML] The interplay between androgens and the immune response in polycystic ovary syndrome

S Shabbir, E Khurram, VS Moorthi, YTH Eissa… - Journal of Translational …, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a metabolic-reproductive-endocrine disorder that,
while having a genetic component, is known to have a complex multifactorial etiology. As …

Efficacy of bariatric surgery in the treatment of women with obesity and polycystic ovary syndrome

L Hu, L Ma, X Xia, T Ying, M Zhou, S Zou… - The Journal of …, 2022 - academic.oup.com
Context The comparative effectiveness of drugs and surgical therapy for women with obesity
and polycystic ovary syndrome (PCOS) has not been systematically compared. Objective …

[HTML][HTML] Oxidative stress and reproductive function: oxidative stress in polycystic ovary syndrome

E Rudnicka, AM Duszewska, M Kucharski… - …, 2022 - rep.bioscientifica.com
In brief A genetic, epigenetic, and environmental association exists between oxidative stress
(OS) and polycystic ovary syndrome (PCOS), expressed in a multifaceted clinical profile …