Estrogen receptor α and β in the normal immune system and in lymphoid malignancies

K Yakimchuk, M Jondal, S Okret - Molecular and cellular endocrinology, 2013 - Elsevier
Estrogens regulate various normal and pathophysiological processes including cancers.
Cellular signaling by estrogens is mediated by estrogen receptor α (ERα) and β (ERβ) …

Ovarian neoplasms in patients with colorectal cancer: understanding the role of prophylactic oophorectomy

NN Hanna, AM Cohen - Clinical Colorectal Cancer, 2004 - Elsevier
Although the role of prophylactic oophorectomy is currently under debate and not well
defined, it is of increasing and considerable relevance, especially in premenopausal …

Investigations on cellular proliferation induced by zearalenone and its derivatives in relation to the estrogenic parameters

F Minervini, A Giannoccaro, A Cavallini, A Visconti - Toxicology letters, 2005 - Elsevier
Many man-made chemicals (pesticides) and naturally occurring compounds (mycotoxins
and phytoestrogens) can enter the food chain and bind to estrogen receptors (ERs) …

Oestrogen receptor-related receptor alpha (ERRα) and oestrogen receptors (ERα and ERβ) exhibit different gene expression in human colorectal tumour progression

A Cavallini, M Notarnicola, R Giannini… - European journal of …, 2005 - Elsevier
We have investigated the presence of oestrogen receptor-related (ERR) mRNA in human
colorectal tumour tissues and adjacent normal mucosa by reverse transcriptase and nested …

ERβ isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates

NACS Wong, RDG Malcomson… - The Journal of …, 2005 - Wiley Online Library
Colorectal carcinoma shows several sex‐related differences with regard to incidence,
response to chemotherapy and microsatellite instability. These differences may relate to …

Estrogen activation by steroid sulfatase increases colorectal cancer proliferation via GPER

LC Gilligan, HP Rahman, AM Hewitt… - The Journal of …, 2017 - academic.oup.com
Context Estrogens affect the incidence and progression of colorectal cancer (CRC),
although the precise molecular mechanisms remain ill-defined. Objective The present study …

Expression analysis of a subset of coregulators and three nuclear receptors in human colorectal carcinoma

R Giannini, A Cavallini - Anticancer Research, 2005 - ar.iiarjournals.org
In human colorectal tissue samples, the gene expressions of 4 coactivators, p300, pCAF, TIF-
2 and TRAP 220, and 7 corepressors, N-CoR, REA, MTA1, MTA1L1, HDAC1, HDAC2 and …

The effects of chronic lifelong activation of the AHR pathway by industrial chemical pollutants on female human reproduction

A Cavallini, C Lippolis, M Vacca, C Nardelli… - PloS one, 2016 - journals.plos.org
Environmental chemicals, such as heavy metals, affect female reproductive function. A
biological sensor of the signals of many toxic chemical compounds seems to be the aryl …

Estrone sulfate transport and steroid sulfatase activity in colorectal cancer: implications for hormone replacement therapy

LC Gilligan, A Gondal, V Tang, MT Hussain… - Frontiers in …, 2017 - frontiersin.org
Hormone replacement therapy (HRT) affects the incidence and potential progression of
colorectal cancer (CRC). As HRT primarily consists of estrone sulfate (E1S), understanding …

Transcriptional analysis of estrogen receptor alpha variant mRNAs in colorectal cancers and their matched normal colorectal tissues

H Jiang, R Teng, Q Wang, X Zhang, H Wang… - The Journal of steroid …, 2008 - Elsevier
Estrogen is involved in suppression of colorectal cancer development and exerts its function
via estrogen receptors α, β and their splicing variants. Whether the recently indentified ER-α …