Macrophages and microglia (M/Ms) in the injured spinal cord maintain a predominantly
neurotoxic M1 phenotype that is disadvantageous to repair in the development of spinal …

Prolonged inflammation after spinal cord injury is detrimental to recovery. To find
pharmacological modulators of the inflammation response, we designed a rapid drug …

Background Blood–spinal cord barrier (BSCB) disruption is a key event after spinal cord
injury (SCI), which permits unfavorable blood-derived substances to enter the neural tissue …

Spinal cord injury (SCI) disrupts neurological pathways and impacts sensory, motor, and
autonomic nerve function. There is no effective treatment for SCI currently. Numerous …

Spinal cord injury (SCI) induced catastrophic neurological disability is currently incurable,
especially for elderly patients. Due to the limited axon regeneration capacity and hostile …

Neuroinflammation plays an important role in secondary injury after spinal cord injury (SCI)
and may aggravate neurological dysfunction. Several studies have indicated that sodium …

Traumatic spinal cord injury (SCI) initiates a cascade of cellular events, culminating in
irreversible tissue loss and neuroinflammation. After the trauma, the blood vessels are …

Degenerative cervical myelopathy (DCM) is caused by age-related degeneration of the
cervical spine, causing chronic spinal cord compression and inflammation. The aim of this …

Spinal cord injury (SCI) is a pathological condition that leading to serious nerve damage,
disability and even death. Increasing evidence have revealed that circular RNAs (circRNAs) …

Individuals with spinal cord injury (SCI) have higher infection rates compared to those
without SCI. In this review, the immune status difference between individuals with and …