[PDF][PDF] Breast cancer genes: beyond BRCA1 and BRCA2

SE Filippini, A Vega - Front Biosci (Landmark Ed), 2013 - article.imrpress.com
[Frontiers in Bioscience 18, 1358-1372, June 1, 2013] 1358 Breast cancer genes: beyond
BRCA1 and BRCA2 Sandra E. Filippini1, 2 a Page 1 [Frontiers in Bioscience 18, 1358-1372 …

Genetic variations in DNA repair genes, radiosensitivity to cancer and susceptibility to acute tissue reactions in radiotherapy-treated cancer patients

DA Chistiakov, NV Voronova, PA Chistiakov - Acta oncologica, 2008 - Taylor & Francis
Ionizing radiation is a well established carcinogen for human cells. At low doses, radiation
exposure mainly results in generation of double strand breaks (DSBs). Radiation-related …

Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival

Q Zheng, SM Dunlap, J Zhu… - Endocrine-related …, 2011 - erc.bioscientifica.com
Papillary thyroid carcinoma (PTC) etiologically occurs as a radiation-induced or sporadic
malignancy. Genetic factors contributing to the susceptibility to either form remain unknown …

[HTML][HTML] Polymorphisms of DNA damage response genes in radiation-related and sporadic papillary thyroid carcinoma

NM Akulevich, VA Saenko… - Endocrine-related …, 2009 - erc.bioscientifica.com
Papillary thyroid carcinoma (PTC) etiologically occurs as a radiation-induced or sporadic
malignancy. Genetic factors contributing to the susceptibility to either form remain unknown …

Ghrelin and lipid metabolism: key partners in energy balance

L Varela, MJ Vázquez, F Cordido… - Journal of …, 2011 - jme.bioscientifica.com
It is widely accepted that thyroid cancer is strongly determined by the individual genetic
background. In this regard, it is expected that sporadic thyroid cancer is the result of multiple …

Single nucleotide polymorphisms in DNA repair genes and putative cancer risk

B Köberle, B Koch, BM Fischer, A Hartwig - Archives of toxicology, 2016 - Springer
Single nucleotide polymorphisms (SNPs) are the most frequent type of genetic alterations
between individuals. An SNP located within the coding sequence of a gene may lead to an …

DNA repair gene XRCC3 polymorphisms and cancer risk: a meta-analysis of 48 case–control studies

S Han, HT Zhang, Z Wang, Y Xie, R Tang… - European journal of …, 2006 - nature.com
The X-ray repair cross-complementing group 3 (XRCC3) is a highly suspected candidate
gene for cancer susceptibility. However, association studies on the XRCC3 polymorphisms …

Defective homologous recombination in human cancers

A Cerbinskaite, A Mukhopadhyay, ER Plummer… - Cancer treatment …, 2012 - Elsevier
Homologous recombination (HR) is a process by which DNA double strand breaks are
repaired through the alignment of homologous sequences of DNA. Interest continues to …

Recent advances in thyroid cancer. In brief

EG Grubbs, TA Rich, G Li… - Current problems …, 2008 - pubmed.ncbi.nlm.nih.gov

Association of polymorphisms in genes of the homologous recombination DNA repair pathway and thyroid cancer risk

HN Bastos, MR Antao, SN Silva, AP Azevedo, I Manita… - Thyroid, 2009 - liebertpub.com
Background: Ionizing radiation exposure has been pointed out as a risk factor for thyroid
cancer. The double-strand breaks induced by this carcinogen are usually repaired by …