Maternal infection with Zika virus (ZIKV) during pregnancy can result in neonatal
abnormalities, including neurological dysfunction and microcephaly. Experimental models of …

Pathogenicity often differs dramatically among even closely related arenavirus species. For
instance, Junín virus (JUNV), the causative agent of Argentine hemorrhagic fever (AHF), is …

Currently, there are no specific therapeutics for flavivirus infections, including dengue virus
(DENV) and Zika virus (ZIKV). In this study, we evaluated extracts from the plants Hedyotis …

Mayaro virus (MAYV) is an emergent arthropod-borne virus that causes an acute febrile
illness accompanied by arthralgia, similar to chikungunya virus. Increasing urbanization of …

A well-tolerated and cost-effective oral drug that blocks SARS-CoV-2 growth and
dissemination would be a major advance in the global effort to reduce COVID-19 morbidity …

Cell-derived influenza vaccines provide better protection and a host of other advantages
compared to the egg-derived vaccines that currently dominate the market, but their …

Antibiotic resistance is one of the greatest threats to modern medicine. Drugs that were once
routinely used to treat infections are being rendered ineffective, increasing the demand for …

Dengue fever is a common arbovirus disease, which has been spread to the entire tropical
world. At present, effective drugs for the treatment of dengue fever have not yet appeared …

Background Reverse genetics systems have been crucial for studying specific viral genes
and their relevance in the virus lifecycle, and become important tools for the rational …

Dengue and Zika viruses co-circulate annually in endemic areas of Mexico, causing
outbreaks of different magnitude and severity every year, suggesting a continuous selection …