Fc-γR-dependent antibody effector functions are required for vaccine-mediated protection against antigen-shifted variants of SARS-CoV-2
Emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with
antigenic changes in the spike protein are neutralized less efficiently by serum antibodies …
antigenic changes in the spike protein are neutralized less efficiently by serum antibodies …
Antigen‐specific and cross‐reactive T cells in protection and disease
Human T cells have a diverse T‐cell receptor (TCR) repertoire that endows them with the
ability to identify and defend against a broad spectrum of antigens. The universe of possible …
ability to identify and defend against a broad spectrum of antigens. The universe of possible …
Dissecting the Protective Effect of CD8+ T Cells in Response to SARS-CoV-2 mRNA Vaccination and the Potential Link with Lymph Node CD8+ T Cells
M Chen, V Venturi, CML Munier - Biology, 2023 - mdpi.com
Simple Summary Coronavirus disease 2019 (COVID-19) is a respiratory disease caused by
the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
Neutralizing antibodies to Omicron after the fourth SARS-CoV-2 mRNA vaccine dose in immunocompromised patients highlight the need of additional boosters
Introduction Immunocompromised patients have been shown to have an impaired immune
response to COVID-19 vaccines. Methods Here we compared the B-cell, T-cell and …
response to COVID-19 vaccines. Methods Here we compared the B-cell, T-cell and …
[HTML][HTML] Fcγ receptor-dependent antibody effector functions are required for vaccine protection against infection by antigenic variants of SARS-CoV-2
Emerging SARS-CoV-2 variants with antigenic changes in the spike protein are neutralized
less efficiently by serum antibodies elicited by legacy vaccines against the ancestral Wuhan …
less efficiently by serum antibodies elicited by legacy vaccines against the ancestral Wuhan …
Integrated antibody and cellular immunity monitoring are required for assessment of the long term protection that will be essential for effective next generation vaccine …
E Paramithiotis, C Varaklis, S Pillet, S Shafiani… - Frontiers in …, 2023 - frontiersin.org
The COVID pandemic exposed the critical role T cells play in initial immunity, the
establishment and maintenance of long term protection, and of durable responsiveness …
establishment and maintenance of long term protection, and of durable responsiveness …
A measles-vectored vaccine candidate expressing prefusion-stabilized SARS-CoV-2 spike protein brought to phase I/II clinical trials: candidate selection in a …
J Brunet, Z Choucha, M Gransagne, H Tabbal… - Journal of …, 2024 - Am Soc Microbiol
In the early COVID-19 pandemic with urgent need for countermeasures, we aimed at
developing a replicating viral vaccine using the highly efficacious measles vaccine as …
developing a replicating viral vaccine using the highly efficacious measles vaccine as …
Importance of Cellular Immunity and IFN-γ Concentration in Preventing SARS-CoV-2 Infection and Reinfection: A Cohort Study
D Primorac, P Brlek, ES Pavelić, J Mešić… - Viruses, 2023 - mdpi.com
Recent studies have highlighted the underestimated importance of the cellular immune
response after the emergence of variants of concern (VOCs) of SARS-CoV-2, and the …
response after the emergence of variants of concern (VOCs) of SARS-CoV-2, and the …
CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH …
Serological correlates of protection against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection after vaccination (“vaccine breakthrough”) have been described …
(SARS-CoV-2) infection after vaccination (“vaccine breakthrough”) have been described …
Leishmaniasis vaccines: applications of RNA technology and targeted clinical trial designs
MS Duthie, BAS Machado, R Badaró, PM Kaye… - Pathogens, 2022 - mdpi.com
Leishmania parasites cause a variety of discrete clinical diseases that present in regions
where their specific sand fly vectors sustain transmission. Clinical and laboratory research …
where their specific sand fly vectors sustain transmission. Clinical and laboratory research …