Background Onychomycosis, the most prevailing affliction of the nail, accounts for
approximately 90% of the toenail infection worldwide. Owing to this infection, the affected …

Iontophoresis is a physical drug delivery enhancing technique that was introduced at the
beginning of the preceding century. For decades, iontophoresis research was focused on …

Inkjet printing (IJP) is an emerging technology for the precision dosing of medicines. We
report, for the first time, the printing of the antifungal drug terbinafine hydrochloride directly …

Purpose Through the characterisation of the human onchomycotic nail plate this study
aimed to inform the design of new topical ungual formulations. Methods The mechanical …

Objective This study is aimed to explore the effectiveness of some novel terpenes as
potential penetration enhancers on transungual delivery of terbinafine. Methods Ex-vivo …

Background Onychomycosis, a fungal infection affecting the nail plate, is a common
condition often requiring prolonged treatment regimens, with low success rates. Urea is one …

In the present study, a new extraction method based on acid digestion and SPE clean-up
(Oasis Wax) was developed for measuring four PFR metabolites (ie dibutyl phosphate …

Fungal diseases have posed a great challenge to global health, but have fewer solutions
compared to bacterial and viral infections. Development and application of new treatment …

Background Treatment of nail psoriasis is disappointing; due to poor penetrability of topical
therapies and variable efficacy of systemic therapies. Fractional carbon dioxide laser (FCL) …

The successful topical therapy of onychomycosis depends on effective drug release and
penetration into nail, which can be achieved by using an adequately developed delivery …