The human lung plays vital roles in respiration, host defense, and basic physiology. Recent
technological advancements such as single-cell RNA sequencing and genetic lineage …

Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation,
predominantly affecting the lung parenchyma and peripheral airways, that results in …

Chronic obstructive pulmonary disease (COPD) is characterized by progressive and
irreversible airflow obstruction with abnormal lung function. Because its pathogenesis …

A variety of intrinsic and extrinsic factors contribute to the altered efficiency of CTLs in elderly
organisms. In particular, the efficacy of antiviral CD8+ T cells responses in the elderly has …

Rationale COPD is characterized by chronic airway inflammation, small airways changes,
with disappearance and obstruction, and also distal/alveolar destruction (emphysema). The …

Purpose Chronic obstructive pulmonary disease (COPD) is a complex and persistent lung
disease and lack of biomarkers. The aim of this study is to screen and verify effective …

Introduction Although different phenotypes of lung disease after preterm birth have recently
been described, the underlying mechanisms associated with each phenotype are poorly …

Rationale: Despite the importance of inflammation in chronic obstructive pulmonary disease
(COPD), the immune cell landscape in the lung tissue of patients with mild-moderate …

Environmental air irritants including nanosized carbon black (nCB) can drive systemic
inflammation, promoting chronic obstructive pulmonary disease (COPD) and emphysema …

Background Virus infections drive COPD exacerbations and progression. Antiviral immunity
centres on the activation of virus-specific CD8+ T-cells by viral epitopes presented on major …