Aims Cortical spreading depolarization (CSD) is a wave of pathologic neuronal dysfunction
that spreads through cerebral gray matter, causing neurologic disturbance in migraine and …

Remote ischaemic conditioning (RIC) refers to a process whereby periods of intermittent
ischaemia, typically via the cyclical application of a blood pressure cuff to a limb at above …

Aims Alzheimer's disease (AD) is a significant global health concern, and it is crucial that we
find effective methods to prevent or slow down AD progression. Recent studies have …

Remote ischemic conditioning (RIC), which involves a series of short cycles of ischemia in
an organ remote to the brain (typically the limbs), has been shown to protect the ischemic …

Background: Chronic cerebral hypoperfusion (CCH) is a clinical syndrome, which is
characterized by significantly decreased cerebral blood flow (CBF). CCH is a common …

Vascular cognitive impairment (VCI) is a heterogeneous disease caused by a variety of
cerebrovascular diseases. Patients with VCI often present with slower cognitive processing …

This study aims to explore the effect of Tectorigenin in chronic cerebral ischemia (CCI)-
induced cognitive impairment mice model. Cognitive impairment, hippocampal tissue …

Ischemic cerebrovascular disease (ICD), the most common neurological disease worldwide,
can be classified based on the onset time (acute/chronic) and the type of cerebral blood …

Background and Purpose Moyamoya disease (MMD) is a complicated cerebrovascular
disease with recurrent ischemic or hemorrhagic events. This study aimed to prove the safety …

Introduction Epigenetic stimuli induce beneficial or detrimental changes in gene expression,
and consequently, phenotype. Some of these phenotypes can manifest across the lifespan …