Sex differences in depression: Insights from clinical and preclinical studies

RS Eid, AR Gobinath, LAM Galea - Progress in neurobiology, 2019 - Elsevier
Depression represents a global mental health concern, and disproportionally affects women
as they are twice more likely to be diagnosed than men. In this review, we provide a …

Unraveling the epigenetic landscape of depression: focus on early life stress

A Torres-Berrío, O Issler, EM Parise… - Dialogues in clinical …, 2019 - Taylor & Francis
Depression is a devastating psychiatric disorder caused by a combination of genetic
predisposition and life events, mainly exposure to stress. Early life stress (ELS) in particular …

A sex-specific genome-wide association study of depression phenotypes in UK Biobank

PP Silveira, I Pokhvisneva, DM Howard… - Molecular …, 2023 - nature.com
There are marked sex differences in the prevalence, phenotypic presentation and treatment
response for major depression. While genome-wide association studies (GWAS) adjust for …

Environmental programming of susceptibility and resilience to stress in adulthood in male mice

CJ Peña, EJ Nestler, RC Bagot - Frontiers in Behavioral …, 2019 - frontiersin.org
Epidemiological evidence identifies early life adversity as a significant risk factor for the
development of mood disorders. Much evidence points to the role of early life experience in …

Hippocampal BDNF in physiological conditions and social isolation

I Zaletel, D Filipović, N Puškaš - Reviews in the Neurosciences, 2017 - degruyter.com
Exposure of an organism to chronic psychosocial stress may affect brain-derived
neurotrophic factor (BDNF) expression that has been implicated in the etiology of psychiatric …

Sex differences in depression and anxiety

P Pavlidi, N Kokras, C Dalla - Sex Differences in Brain Function and …, 2022 - Springer
Depression and anxiety disorders carry a tremendous worldwide burden and emerge as a
significant cause of disability among western societies. Both disorders are known to …

An overview of the heterogeneity of major depressive disorder: current knowledge and future prospective

KV Athira, S Bandopadhyay… - Current …, 2020 - ingentaconnect.com
Major depressive disorder (MDD) is estimated to impose maximum debilitating effects on the
society by 2030, with its critical effects on health, functioning, quality of life and concomitant …

The shaping of science by ideology: How feminism inspired, led, and constrained scientific understanding of sex and gender

AH Eagly - Journal of Social Issues, 2018 - Wiley Online Library
Abstract When the Second Wave of feminism emerged in the 1960s and 1970s, feminist
psychologists vigorously attacked earlier scholarship on gender for assuming that women's …

Astroglia in the vulnerability to and maintenance of stress-mediated neuropathology and depression

JJ Miguel-Hidalgo - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Significant stress exposure and psychiatric depression are associated with morphological,
biochemical, and physiological disturbances of astrocytes in specific brain regions relevant …

[HTML][HTML] The influence of parenting styles and parental depression on adolescent depressive symptoms: A cross-sectional and longitudinal approach

R Keijser, S Olofsdotter, KW Nilsson… - Mental Health & Prevention, 2020 - Elsevier
Background Depression often emerges during early adolescence and is one of the most
common mental health problems. The present study investigated the influence of parenting …