In the last decades, a lot of attention has been paid to the compounds present in medicinal
Cannabis sativa L., such as Δ9‐tetrahydrocannabinol (Δ9‐THC) and cannabidiol (CBD) …

There is growing recognition that B cell contributions to normal immune responses extend
well beyond their potential to become antibody-producing cells, including roles at the innate …

Multiple sclerosis (MS) is a neurologic disease affecting myelinated nerves in the central
nervous system (CNS). The disease often debuts as a clinically isolated syndrome, eg, optic …

Granulocyte-macrophage colony-stimulating factor (GM-CSF) was first described as a
growth factor that induces the differentiation and proliferation of myeloid progenitors in the …

The gut microbiome plays an important role in immune function and has been implicated in
multiple sclerosis (MS). However, how and if the modulation of microbiota can prevent or …

Microglia are the resident innate immune cells of the central nervous system (CNS)
parenchyma. To determine the impact of microglia on disease development and progression …

Despite the availability of a lot of effective disease-modifying drugs, multiple sclerosis
(MS)(in particular the progressive forms) still represents an important unmet medical need …

Multiple sclerosis (MS) is a chronic inflammatory disease that is characterized by leukocyte
infiltration and subsequent axonal damage, demyelinating inflammation, and formation of …

Breakdown of the blood-brain barrier (BBB) precedes lesion formation in the brains of
multiple sclerosis (MS) patients. Since recent data implicate disruption of the small intestinal …

Multiple sclerosis (MS) is a chronic, inflammatory, and degenerative disease of the central
nervous system (CNS). Inflammation is observed in all stages of MS, both within and around …