Interleukin-1 beta—a friend or foe in malignancies?
R Bent, L Moll, S Grabbe, M Bros - International journal of molecular …, 2018 - mdpi.com
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune
cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after …
cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after …
The role of interleukin-1 in general pathology
N Kaneko, M Kurata, T Yamamoto, S Morikawa… - Inflammation and …, 2019 - Springer
Abstract Interleukin-1, an inflammatory cytokine, is considered to have diverse physiological
functions and pathological significances and play an important role in health and disease. In …
functions and pathological significances and play an important role in health and disease. In …
Cutting edge: Mycobacterium tuberculosis induces aerobic glycolysis in human alveolar macrophages that is required for control of intracellular bacillary replication
LE Gleeson, FJ Sheedy… - The Journal of …, 2016 - journals.aai.org
Recent advances in immunometabolism link metabolic changes in stimulated macrophages
to production of IL-1β, a crucial cytokine in the innate immune response to Mycobacterium …
to production of IL-1β, a crucial cytokine in the innate immune response to Mycobacterium …
Immunoevasion and immunosuppression of the macrophage by Mycobacterium tuberculosis
Z Hmama, S Peña‐Díaz, S Joseph… - Immunological …, 2015 - Wiley Online Library
By virtue of their position at the crossroads between the innate and adaptive immune
response, macrophages play an essential role in the control of bacterial infections …
response, macrophages play an essential role in the control of bacterial infections …
Single-cell RNA sequencing reveals cellular and transcriptional changes associated with M1 macrophage polarization in hidradenitis suppurativa
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by
recurrent abscesses, nodules, and sinus tracts in areas of high hair follicle and sweat gland …
recurrent abscesses, nodules, and sinus tracts in areas of high hair follicle and sweat gland …
Paclitaxel enhances the innate immunity by promoting NLRP3 inflammasome activation in macrophages
Q Zeng, F Yang, C Li, L Xu, X He, F Mai… - Frontiers in …, 2019 - frontiersin.org
Microtubules play critical roles in regulating the activation of NLRP3 inflammasome and
microtubule-destabilizing agents such as colchicine have been shown to suppress the …
microtubule-destabilizing agents such as colchicine have been shown to suppress the …
Immune mechanisms of plaque instability
T Gerhardt, A Haghikia, P Stapmanns… - Frontiers in …, 2022 - frontiersin.org
Inflammation crucially drives atherosclerosis from disease initiation to the emergence of
clinical complications. Targeting pivotal inflammatory pathways without compromising the …
clinical complications. Targeting pivotal inflammatory pathways without compromising the …
Interaction between gut microbiota and immune checkpoint inhibitor-related colitis
G Zhou, N Zhang, K Meng, F Pan - Frontiers in Immunology, 2022 - frontiersin.org
Immune checkpoint inhibitors (ICIs) have become a promising therapeutic strategy for
malignant tumors, improving patient prognosis, along with a spectrum of immune-related …
malignant tumors, improving patient prognosis, along with a spectrum of immune-related …
Desferrioxamine Supports Metabolic Function in Primary Human Macrophages Infected With Mycobacterium tuberculosis
Tuberculosis is the single biggest infectious killer in the world and presents a major global
health challenge. Antimicrobial therapy requires many months of multiple drugs and …
health challenge. Antimicrobial therapy requires many months of multiple drugs and …
[HTML][HTML] Intermediate monocytes induced by IFN-γ inhibit cancer metastasis by promoting NK cell activation through FOXO1 and interleukin-27
R Wang, W Bao, M Pal, Y Liu… - … for ImmunoTherapy of …, 2022 - ncbi.nlm.nih.gov
Background Circulating monocytes are functionally heterogeneous and can be divided into
classical (CMo), intermediate (IMo), and non-CMo/patrolling monocyte (PMo) subsets. CMo …
classical (CMo), intermediate (IMo), and non-CMo/patrolling monocyte (PMo) subsets. CMo …