Type IV pili: dynamics, biophysics and functional consequences

L Craig, KT Forest, B Maier - Nature reviews microbiology, 2019 - nature.com
The surfaces of many bacteria are decorated with long, exquisitely thin appendages called
type IV pili (T4P), dynamic filaments that are rapidly polymerized and depolymerized from a …

[HTML][HTML] Gonorrhoea

M Unemo, HS Seifert, EW Hook III, S Hawkes… - Nature Reviews …, 2019 - nature.com
The bacterium Neisseria gonorrhoeae causes the sexually transmitted infection (STI)
gonorrhoea, which has an estimated global annual incidence of 86.9 million adults …

Host range of antibiotic resistance genes in wastewater treatment plant influent and effluent

J Hultman, M Tamminen, K Pärnänen… - FEMS microbiology …, 2018 - academic.oup.com
Wastewater treatment plants (WWTPs) collect wastewater from various sources for a multi-
step treatment process. By mixing a large variety of bacteria and promoting their proximity …

Neisseria gonorrhoeae: Drug Resistance, Mouse Models, and Vaccine Development

PA Rice, WM Shafer, S Ram… - Annual review of …, 2017 - annualreviews.org
Gonorrhea, an obligate human infection, is on the rise worldwide and gonococcal strains
resistant to many antibiotics are emerging. Appropriate antimicrobial treatment and …

[HTML][HTML] Immune responses to Neisseria gonorrhoeae and implications for vaccine development

T Belcher, CS Rollier, C Dold, JDC Ross… - Frontiers in …, 2023 - frontiersin.org
Neisseria gonorrheoae is the causative agent of gonorrhea, a sexually transmitted infection
responsible for a major burden of disease with a high global prevalence. Protective …

Defining heterogeneity within bacterial populations via single cell approaches

KM Davis, RR Isberg - Bioessays, 2016 - Wiley Online Library
Bacterial populations are heterogeneous, which in many cases can provide a selective
advantage during changes in environmental conditions. In some instances, heterogeneity …

[HTML][HTML] Progress toward a gonococcal vaccine: the way forward

MW Russell, AE Jerse, SD Gray-Owen - Frontiers in immunology, 2019 - frontiersin.org
The concept of immunizing against gonorrhea has received renewed interest because of the
recent emergence of strains of Neisseria gonorrhoeae that are resistant to most currently …

[HTML][HTML] Buried treasure: evolutionary perspectives on microbial iron piracy

MF Barber, NC Elde - Trends in Genetics, 2015 - cell.com
Host–pathogen interactions provide valuable systems for the study of evolutionary genetics
and natural selection. The sequestration of essential iron has emerged as a crucial innate …

[PDF][PDF] Intermittent pili-mediated forces fluidize Neisseria meningitidis aggregates promoting vascular colonization

D Bonazzi, VL Schiavo, S Machata, I Djafer-Cherif… - Cell, 2018 - cell.com
Neisseria meningitidis, a bacterium responsible for meningitis and septicemia, proliferates
and eventually fills the lumen of blood capillaries with multicellular aggregates. The impact …

[PDF][PDF] Commensal Neisseria kill Neisseria gonorrhoeae through a DNA-dependent mechanism

WJ Kim, D Higashi, M Goytia, MA Rendón… - Cell host & …, 2019 - cell.com
The mucosa is colonized with commensal Neisseria. Some of these niches are sites of
infection for the STD pathogen Neisseria gonorrhoeae (Ngo). Given the antagonistic …