Elucidating the clonal relationship of esophageal second primary tumors in patients with laryngeal squamous cell carcinoma

M Wan, X Yang, L He, H Meng - Infectious Agents and Cancer, 2023 - Springer
Laryngeal cancer ranks as the second most prevalent upper airway malignancy, following
Lung cancer. Although some progress has been made in managing laryngeal cancer, the 5 …

Circulating tumor DNA dynamics as prognostic markers in locally advanced and metastatic esophageal squamous cell carcinoma

HY Ng, JMY Ko, KO Lam, DLW Kwong, AWI Lo… - JAMA …, 2023 - jamanetwork.com
Importance Esophageal squamous cell carcinoma (ESCC) is a deadly disease with frequent
recurrence. There are unmet needs for prognostic biomarkers for dynamically monitoring …

ALDH2 mutations and defense against genotoxic aldehydes in cancer and inherited bone marrow failure syndromes

AYH Woo, L Jia - … Research-Fundamental and Molecular Mechanisms of …, 2024 - Elsevier
Reactive aldehydes, for instance, formaldehyde and acetaldehyde, are important
endogenous or environmental mutagens by virtue of their abilities to produce a DNA lesion …

Successful surgery with preservation of laryngeal function in a patient with collision primary squamous cell carcinoma and adenoid cystic carcinoma in the …

Z Fu, X Xu, Y Bao, Z Chen, J Zhong, S Zhou - Head & Neck, 2023 - Wiley Online Library
Background The definition of “collision tumor” is the coexistence of two histologically and
morphologically distinct tumors within the same anatomical area without histological …

Ethanol induces replication fork stalling and membrane stress in immortalized laryngeal cells

L Hoes, K Voordeckers, R Dok, B Boeckx, B Steemans… - Iscience, 2023 - cell.com
Although ethanol is a class I carcinogen and is linked to more than 700,000 cancer
incidences, a clear understanding of the molecular mechanisms underlying ethanol-related …

Molecular landscapes of oral cancers of unknown etiology

S Deneuve, B Fervers, S Senkin, L Bouaoun, O Pérol… - medRxiv, 2023 - medrxiv.org
The incidence of the mobile tongue cancer in young patients has been rising. This oral
cancer (OC) type has no identified risk factors (NIRF), no established molecular markers and …

Applications of single-cell sequencing in upper and lower airway diseases: progress and perspectives

H Liu, J Yin, Y Yang, X Xu, J Yu, X Luo… - Authorea …, 2023 - essopenarchive.org
Single-cell sequencing (SCS), including genomic, transcriptomic, epigenomic, proteomic,
and metabolomic sequencing, is a powerful tool for revealing cellular and molecular …