[HTML][HTML] Hydrogels for exosome delivery in biomedical applications

Y Xie, Q Guan, J Guo, Y Chen, Y Yin, X Han - Gels, 2022 - mdpi.com
Hydrogels, which are hydrophilic polymer networks, have attracted great attention, and
significant advances in their biological and biomedical applications, such as for drug …

[HTML][HTML] Exosomes and exosomal cargos: a promising world for ventricular remodeling following myocardial infarction

J Fang, Y Zhang, D Chen, Y Zheng… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Exosomes are a pluripotent group of extracellular nanovesicles secreted by all cells that
mediate intercellular communications. The effective information within exosomes is primarily …

Engineered exosome for drug delivery: recent development and clinical applications

J Tian, Z Han, D Song, Y Peng, M Xiong… - International Journal …, 2023 - Taylor & Francis
Exosomes are nano-sized membrane vesicles that transfer bioactive molecules between
cells and modulate various biological processes under physiological and pathological …

[HTML][HTML] Can extracellular vesicles as drug delivery systems be a game changer in cardiac disease?

A Okamura, Y Yoshioka, Y Saito, T Ochiya - Pharmaceutical Research, 2023 - Springer
Cardiac diseases such as myocardial infarction and heart failure have been the leading
cause of death worldwide for more than 20 years, and new treatments continue to be …

[HTML][HTML] A 3D culture system improves the yield of MSCs-derived extracellular vesicles and enhances their therapeutic efficacy for heart repair

L Sun, Y Ji, B Chi, T Xiao, C Li, X Yan, X Xiong… - Biomedicine & …, 2023 - Elsevier
Abstract Background Extracellular vesicles (EVs) derived from mesenchymal stem cells
(MSCs), due to their inner functional substances, have shown great value in treating acute …

Exosome-bearing hydrogels and cardiac tissue regeneration

H Amini, AR Namjoo, MT Narmi, N Mardi… - Biomaterials …, 2023 - spj.science.org
Background In recent years, cardiovascular disease in particular myocardial infarction (MI)
has become the predominant cause of human disability and mortality in the clinical setting …

[HTML][HTML] Endothelialization and smooth muscle cell regeneration capabilities of a bi-layered small diameter vascular graft for blood vessel reconstruction

MA Al Fahad, MS Rahaman, MSI Mahbub, M Park… - Materials & Design, 2023 - Elsevier
Despite the tremendous advances in the past few decades, the clinical problems associated
with low mechanical strength, thrombosis, and inadequate endothelialization still have not …

Nicorandil-Pretreated Mesenchymal Stem Cell-Derived Exosomes Facilitate Cardiac Repair After Myocardial Infarction via Promoting Macrophage M2 Polarization by …

ZT Gong, YY Xiong, Y Ning, RJ Tang… - International Journal …, 2024 - Taylor & Francis
Background Exosomes derived from bone marrow mesenchymal stem cells (MSC-exo) have
been considered as a promising cell-free therapeutic strategy for ischemic heart disease …

The beneficial effects of mesenchymal stem cells and their exosomes on myocardial infarction and critical considerations for enhancing their efficacy

M Ala - Ageing Research Reviews, 2023 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stromal cells with regenerative, anti-
inflammatory, and immunomodulatory properties. MSCs and their exosomes significantly …

[HTML][HTML] Cardiac tissue engineering for myocardial infarction treatment

P Gil-Cabrerizo, I Scacchetti, E Garbayo… - European Journal of …, 2023 - Elsevier
Myocardial infarction is one of the major causes of morbidity and mortality worldwide.
Current treatments can relieve the symptoms of myocardial ischemia but cannot repair the …