Peptide nucleic acids: Advanced tools for biomedical applications

A Gupta, A Mishra, N Puri - Journal of biotechnology, 2017 - Elsevier
Abstract Peptide Nucleic Acids (PNAs) are the DNA/RNA analogues in which sugar-
phosphate backbone is replaced by N-2-aminoethylglycine repeating units. PNA contains …

Fluorogenic PNA probes

T Vilaivan - Beilstein Journal of Organic Chemistry, 2018 - beilstein-journals.org
Fluorogenic oligonucleotide probes that can produce a change in fluorescence signal upon
binding to specific biomolecular targets, including nucleic acids as well as non-nucleic acid …

Neutralized chimeric DNA probe for detection of single nucleotide polymorphism on surface plasmon resonance biosensor

CJ Huang, ZE Lin, YS Yang, HWH Chan… - Biosensors and …, 2018 - Elsevier
An implementation of neutralized chimeric DNA oligomer as a probe for sensitive detection
of single nucleotide polymorphisms (SNPs) on a surface plasmon resonance imaging …

Whole genome sequence analysis indicates recent diversification of mammal-associated Campylobacter fetus and implicates a genetic factor associated with H2S …

L van der Graaf–van Bloois, B Duim, WG Miller… - BMC genomics, 2016 - Springer
Background Campylobacter fetus (C. fetus) can cause disease in both humans and animals.
C. fetus has been divided into three subspecies: C. fetus subsp. fetus (Cff), C. fetus subsp …

A peptide nucleic acid probe-based multiplex qPCR assay for rapid and accurate detection and quantification of fish-pathogenic Edwardsiella species

A Kim, M Jang, HJ Lim, CY Kim, JY Song, MY Cho - Aquaculture, 2024 - Elsevier
Edwardsiellosis causes severe economic losses in the aquaculture industry worldwide.
Accurate identification of the fish pathogenic Edwardsiella species is crucial for preventing …

Neutralized chimeric DNA probe for the improvement of GC-rich RNA detection specificity on the nanowire field-effect transistor

WC Chou, WP Hu, YS Yang, HWH Chan, WY Chen - Scientific reports, 2019 - nature.com
Silicon nanowire (SiNW) field-effect transistors (FETs) is a powerful tool in genetic molecule
analysis because of their high sensitivity, short detection time, and label-free detection. In …

Microsatellite instability test using peptide nucleic acid probe-mediated melting point analysis: a comparison study

M Jang, Y Kwon, H Kim, H Kim, BS Min, Y Park, TI Kim… - Bmc Cancer, 2018 - Springer
Background Analysis of high microsatellite instability (MSI-H) phenotype in colorectal
carcinoma (CRC) is important for evaluating prognosis and choosing a proper adjuvant …

Novel method of real-time PCR-based screening for common fetal trisomies

SY Kim, SM Lee, SM Kim, BJ Kim, JN Koo, IH Oh… - BMC Medical …, 2021 - Springer
Background The non-invasive prenatal test (NIPT) is based on next generation sequencing
(NGS) and is used for screening for fetal trisomy. However, it is time-consuming and …

Development of a novel real-time RT-PCR method using peptide nucleic acid (PNA) probes for detecting and genotyping of viral haemorrhagic septicaemia virus …

HJ Kim, SR Kwon, NJ Olesen, A Cuenca - Aquaculture, 2023 - Elsevier
Viral haemorrhagic septicaemia (VHS) is one of the most serious viral diseases in salmonid
and olive flounder farms. The causative agent of VHS is the VHS virus (VHSV), which has …

Bioinformatic tools and guidelines for the design of fluorescence in situ hybridization probes

H Teixeira, AL Sousa, AS Azevedo - Fluorescence in-situ hybridization …, 2021 - Springer
Fluorescence in situ hybridization (FISH) is a well-established technique that allows the
detection of microorganisms in diverse types of samples (eg, clinical, food, environmental …