Screening embryos for polygenic disease risk: a review of epidemiological, clinical, and ethical considerations

A Capalbo, G de Wert, H Mertes… - Human reproduction …, 2024 - academic.oup.com
BACKGROUND The genetic composition of embryos generated by in vitro fertilization (IVF)
can be examined with preimplantation genetic testing (PGT). Until recently, PGT was limited …

Perspectives of preimplantation genetic testing patients in Belgium on the ethics of polygenic embryo screening

M Siermann, JR Vermeesch, T Raivio, A Vanhie… - Reproductive …, 2024 - Elsevier
Research question What are the perspectives of preimplantation genetic testing (PGT)
patients in Belgium on the ethics of PGT for polygenic risk scoring (PGT-P)? Design In-depth …

Polygenic embryo screening: quo vadis?

M Siermann, JR Vermeesch, T Raivio, O Tšuiko… - Journal of Assisted …, 2024 - Springer
Recently, the use of polygenic risk scores in embryo screening (PGT-P) has been introduced
on the premise of reducing polygenic disease risk through embryo selection. However, it has …

Tackling real-world issues in human ARTs-the missing link between stakeholders

DF Albertini - Journal of Assisted Reproduction and Genetics, 2024 - Springer
Few would argue about the troubling tenor of a past and current dialogue between
stakeholders across the ART/MAR (medically assisted reproduction) landscape. Be they REI …