Nanomaterial-based drug delivery systems (NBDDS) are widely used to improve the safety
and therapeutic efficacy of encapsulated drugs due to their unique physicochemical and …

Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …

The prognosis of brain cancers such as glioblastoma remains poor despite numerous
advancements in the field of neuro-oncology. The presence of the blood brain barrier (BBB) …

Bacterial infections are a significant cause of mortality and morbidity worldwide, despite
decades of use of numerous existing antibiotics and constant efforts by researchers to …

Nanocarriers have become an effective strategy to overcome epithelial absorption barriers.
During the absorption process, the endocytosis mechanisms, cell internalization pathways …

Bacterial infection has been a major threat to worldwide human health, in particular with the
ever-increasing level of antimicrobial resistance. Given the complex microenvironment of …

Oral delivery is the preferred route of drug administration due to patient compliance and
convenience. Despite this, nanomedicines have so far primarily been developed for the …

Nanoparticle based permeation enhancers have the potential to improve the oral delivery of
biologics. Recently, solid silica nanoparticles were discovered to improve the intestinal …

Antibiotic resistance has become a global threat to health due to abuse of antibiotics. Lots of
existing antibiotics have lost their effect on drug resistant bacteria. Moreover, the discovery …

Vancomycin is the last resort antibiotic for the treatment of severe bacterial keratitis. Its
clinical application is limited due to its hydrophilicity and high molecular weight. To …