Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

An allostatic theory of oxytocin

DS Quintana, AJ Guastella - Trends in cognitive sciences, 2020 - cell.com
Oxytocin has garnered considerable interest for its role in social behavior, as well as for the
potential of intranasal administration to treat social difficulties. However, current theoretical …

Suboptimality in perceptual decision making

D Rahnev, RN Denison - Behavioral and brain sciences, 2018 - cambridge.org
Human perceptual decisions are often described as optimal. Critics of this view have argued
that claims of optimality are overly flexible and lack explanatory power. Meanwhile …

Is testosterone linked to human aggression? A meta-analytic examination of the relationship between baseline, dynamic, and manipulated testosterone on human …

SN Geniole, BM Bird, JS McVittie, RB Purcell… - Hormones and …, 2020 - Elsevier
Testosterone is often considered a critical regulator of aggressive behaviour. There is
castration/replacement evidence that testosterone indeed drives aggression in some …

Oxytocin and the neurobiology of prosocial behavior

N Marsh, AA Marsh, MR Lee… - The …, 2021 - journals.sagepub.com
Humans are an unusually prosocial species, who engage in social behaviors that include
altruism—whereby an individual engages in costly or risky acts to improve the welfare of …

A registered replication study on oxytocin and trust

CH Declerck, C Boone, L Pauwels, B Vogt… - Nature Human …, 2020 - nature.com
In an influential paper, Kosfeld et al.(2005) showed that intranasal administration of oxytocin
(OT) increases the transfers made by investors in the trust game—suggesting that OT …

Infrequent intranasal oxytocin followed by positive social interaction improves symptoms in autistic children: a pilot randomized clinical trial

J Le, L Zhang, W Zhao, S Zhu, C Lan, J Kou… - Psychotherapy and …, 2022 - karger.com
Introduction: There are currently no approved drug interventions for social behavior
dysfunction in autism spectrum disorder (ASD). Previous trials investigating effects of daily …

Oxytocin and pain perception: from animal models to human research

S Boll, ACA De Minas, A Raftogianni, SC Herpertz… - Neuroscience, 2018 - Elsevier
An accumulating body of evidence suggests that the hypothalamic neuropeptide oxytocin
(OT) has a modulatory effect on pain processing. Particularly strong evidence comes from …

Oxytocin—a social peptide? Deconstructing the evidence

G Leng, RI Leng, M Ludwig - … Transactions of the …, 2022 - royalsocietypublishing.org
In this paper, we analyse the claim that oxytocin is a 'social neuropeptide'. This claim
originated from evidence that oxytocin was instrumental in the initiation of maternal …

Effect of a novel nasal oxytocin spray with enhanced bioavailability on autism: a randomized trial

H Yamasue, M Kojima, H Kuwabara, M Kuroda… - Brain, 2022 - academic.oup.com
Although intranasal oxytocin is expected to be a novel therapy for the core symptoms of
autism spectrum disorder, which has currently no approved medication, the efficacy of …