MicroRNAs (miRNAs) are critical regulators of gene expression. As miRNAs are frequently
deregulated in many human diseases, including cancer and immunological disorders, it is …

The finding that small non-coding RNAs (ncRNAs) are able to control gene expression in a
sequence specific manner has had a massive impact on biology. Recent improvements in …

The widespread implementation of mass sequencing has revealed a diverse landscape of
small RNAs derived from larger precursors. Whilst many of these are likely to be byproducts …

A variety of small RNAs, including the Dicer-dependent miRNAs and the Dicer-independent
Piwi-interacting RNAs, associate with Argonaute family proteins to regulate gene expression …

It is largely recognized that microRNAs (miRNAs) function to silence gene expression by
targeting 3′ UTR regions. However, miRNAs have also been implicated to positively …

Spermatogenesis is a cyclic process in which diploid spermatogonia differentiate into
haploid spermatozoa. This process is highly regulated, notably at the post-transcriptional …

MicroRNAs (miRNAs) are a class of genome-encoded small RNAs that are primarily
considered to be post-transcriptional negative regulators of gene expression acting in the …

Synthetic small duplex RNAs that are fully complementary to gene promoters can silence
transcription in mammalian cells. microRNAs (miRNAs) are endogenous small regulatory …

microRNAs (miRNAs) are small, non-coding RNAs with critical roles in fine-tuning a wide
array of biological processes including development, metabolism, and homeostasis …

Small RNA molecules, such as microRNA and small interfering RNA, have emerged as
master regulators of gene expression through their ability to suppress target genes in a …