Abstract Treatment outcomes for major depressive disorder (MDD) need to be improved.
Presently, no clinically relevant tools have been established for stratifying subgroups or …

Stress is viewed as a state of real or perceived threat to homeostasis, the management of
which involves the endocrine, nervous, and immune systems. These systems work …

Probiotics are live microorganisms, which when administered in adequate amounts, present
a health benefit for the host. While the beneficial effects of probiotics on gastrointestinal …

During pregnancy, programming of the fetal central nervous system establishes
vulnerabilities for emergence of neuropsychiatric phenotypes later in life. Psychosocial …

Animals susceptible to chronic social defeat stress (CSDS) exhibit depression-related
behaviors, with aberrant transcription across several limbic brain regions, most notably in …

Abstract Purpose of Review To evaluate the degree to which recent studies provide
evidence that the effects of prenatal maternal stress (PNMS) on child health outcomes vary …

Non-invasive peripheral biomarkers play a significant role in both disease diagnosis and
progression. In the past few years, microRNA (miRNA) expression changes in circulating …

The past decade has revealed neuroinflammation as an important mechanism of major
depressive disorder (MDD). Nod-like receptors family pyrin domain containing 3 (NLRP3) …

Women are roughly twice as likely as men to suffer from stress-related disorders, especially
major depression and generalized anxiety. Accumulating evidence suggest that microbes …

Animal models of psychiatric disorders have been highly effective in advancing the field,
identifying circuits related to pathophysiology, and identifying novel therapeutic targets. In …