Naringin and naringenin as anticancer agents and adjuvants in cancer combination therapy: Efficacy and molecular mechanisms of action, a comprehensive narrative …
Z Memariani, SQ Abbas, SS Ul Hassan… - Pharmacological …, 2021 - Elsevier
Although the rates of many cancers are controlled in Western countries, those of some
cancers, such as lung, breast, and colorectal cancer are currently increasing in many low …
cancers, such as lung, breast, and colorectal cancer are currently increasing in many low …
[HTML][HTML] Effect of citrus flavonoids, naringin and naringenin, on metabolic syndrome and their mechanisms of action
Flavonoids are important natural compounds with diverse biologic activities. Citrus
flavonoids constitute an important series of flavonoids. Naringin and its aglycone naringenin …
flavonoids constitute an important series of flavonoids. Naringin and its aglycone naringenin …
A call for systematic research on solute carriers
A Cesar-Razquin, B Snijder, T Frappier-Brinton… - Cell, 2015 - cell.com
Solute carrier (SLC) membrane transport proteins control essential physiological functions,
including nutrient uptake, ion transport, and waste removal. SLCs interact with several …
including nutrient uptake, ion transport, and waste removal. SLCs interact with several …
Intestinal permeability and drug absorption: predictive experimental, computational and in vivo approaches
D Dahlgren, H Lennernäs - Pharmaceutics, 2019 - mdpi.com
The main objective of this review is to discuss recent advancements in the overall
investigation and in vivo prediction of drug absorption. The intestinal permeability of an …
investigation and in vivo prediction of drug absorption. The intestinal permeability of an …
Transporters and drug-drug interactions: important determinants of drug disposition and effects
Uptake and efflux transporters determine plasma and tissue concentrations of a broad
variety of drugs. They are localized in organs such as small intestine, liver, and kidney …
variety of drugs. They are localized in organs such as small intestine, liver, and kidney …
Fingerprinting food: current technologies for the detection of food adulteration and contamination
Major food adulteration and contamination events seem to occur with some regularity, such
as the widely publicised adulteration of milk products with melamine and the recent …
as the widely publicised adulteration of milk products with melamine and the recent …
Histamine and H1-antihistamines: celebrating a century of progress
FER Simons, KJ Simons - Journal of Allergy and Clinical Immunology, 2011 - Elsevier
In this review we celebrate a century of progress since the initial description of the
physiologic and pathologic roles of histamine and 70 years of progress since the …
physiologic and pathologic roles of histamine and 70 years of progress since the …
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug–drug interactions
M Karlgren, A Vildhede, U Norinder… - Journal of medicinal …, 2012 - ACS Publications
The hepatic organic anion transporting polypeptides (OATPs) influence the
pharmacokinetics of several drug classes and are involved in many clinical drug–drug …
pharmacokinetics of several drug classes and are involved in many clinical drug–drug …
Intestinal drug transporters: an overview
The importance of drug transporters as one of the determinants of pharmacokinetics has
become increasingly evident [1]. While much research has been conducted focusing the role …
become increasingly evident [1]. While much research has been conducted focusing the role …
A review of food–drug interactions on oral drug absorption
Food effect, also known as food–drug interactions, is a common phenomenon associated
with orally administered medications and can be defined as changes in absorption rate or …
with orally administered medications and can be defined as changes in absorption rate or …