Systems biology of malaria explored with nonhuman primates

MR Galinski - Malaria journal, 2022 - Springer
Abstract “The Primate Malarias” book has been a uniquely important resource for multiple
generations of scientists, since its debut in 1971, and remains pertinent to the present day …

[HTML][HTML] Plasmodium vivax gametocytes and transmission

S Bantuchai, H Imad, W Nguitragool - Parasitology International, 2022 - Elsevier
Malaria elimination means cessation of parasite transmission. At present, the declining
malaria incidence in many countries has made elimination a feasible goal. Transmission …

Alternative Invasion Mechanisms and Host Immune Response to Plasmodium vivax Malaria: Trends and Future Directions

D Kepple, K Pestana, J Tomida, A Abebe, L Golassa… - Microorganisms, 2020 - mdpi.com
Plasmodium vivax malaria is a neglected tropical disease, despite being more
geographically widespread than any other form of malaria. The documentation of P. vivax …

Single-cell RNA profiling of Plasmodium vivax-infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targets

AA Ruberto, SP Maher, A Vantaux… - Frontiers in Cellular …, 2022 - frontiersin.org
The resilience of Plasmodium vivax, the most widely-distributed malaria-causing parasite in
humans, is attributed to its ability to produce dormant liver forms known as hypnozoites …

Reduced polymorphism of Plasmodium vivax early transcribed membrane protein (PvETRAMP) 11.2

E Perrotti, M L'episcopia, M Menegon, IS Soares… - Parasites & …, 2023 - Springer
Abstract Background ETRAMP11. 2 (PVX_003565) is a well-characterized protein with
antigenic potential. It is considered to be a serological marker for diagnostic tools, and it has …

The global transcriptome of Plasmodium falciparum mid-stage gametocytes (stages II–IV) appears largely conserved and gametocyte-specific gene expression …

JA Kengne-Ouafo, SY Bah, A Kemp… - Microbiology …, 2023 - Am Soc Microbiol
Our overall understanding of the developmental biology of malaria parasites has been
greatly enhanced by recent advances in transcriptomic analysis. However, most of these …

Long read single cell RNA sequencing reveals the isoform diversity of Plasmodium vivax transcripts

B Hazzard, JM Sá, AC Ellis, TV Pascini… - PLOS Neglected …, 2022 - journals.plos.org
Plasmodium vivax infections often consist of heterogenous populations of parasites at
different developmental stages and with distinct transcriptional profiles, which complicates …

Single-cell RNA sequencing of Plasmodium vivax sporozoites reveals stage- and species-specific transcriptomic signatures

AA Ruberto, C Bourke, A Vantaux… - PLOS Neglected …, 2022 - journals.plos.org
Background Plasmodium vivax sporozoites reside in the salivary glands of a mosquito
before infecting a human host and causing malaria. Previous transcriptome-wide studies in …

Band 3–mediated Plasmodium vivax invasion is associated with transcriptional variation in PvTRAg genes

K De Meulenaere, SK Prajapati, E Villasis… - Frontiers in cellular …, 2022 - frontiersin.org
The Plasmodium vivax reticulocyte invasion process is still poorly understood, with only a
few receptor-ligand interactions identified to date. Individuals with the Southeast Asian …

Single-cell RNA sequencing reveals developmental heterogeneity among Plasmodium berghei sporozoites

AA Ruberto, C Bourke, N Merienne, T Obadia… - Scientific reports, 2021 - nature.com
In the malaria-causing parasite's life cycle, Plasmodium sporozoites must travel from the
midgut of a mosquito to the salivary glands before they can infect a mammalian host …