Neuroprotective effect of antioxidants in the brain

KH Lee, M Cha, BH Lee - International journal of molecular sciences, 2020 - mdpi.com
The brain is vulnerable to excessive oxidative insults because of its abundant lipid content,
high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) …

Desiccation tolerance: avoiding cellular damage during drying and rehydration

MJ Oliver, JM Farrant, HWM Hilhorst… - Annual review of …, 2020 - annualreviews.org
Desiccation of plants is often lethal but is tolerated by the majority of seeds and by
vegetative tissues of only a small number of land plants. Desiccation tolerance is an ancient …

Role of vitamin E as a lipid-soluble peroxyl radical scavenger: in vitro and in vivo evidence

E Niki - Free Radical Biology and Medicine, 2014 - Elsevier
Multiple reactive oxygen/nitrogen species induce oxidative stress. Mammals have evolved
with an elaborate defense network against oxidative stress, in which multiple antioxidant …

Vascular cell adhesion molecule-1 expression and signaling during disease: regulation by reactive oxygen species and antioxidants

JM Cook-Mills, ME Marchese… - Antioxidants & redox …, 2011 - liebertpub.com
The endothelium is immunoregulatory in that inhibiting the function of vascular adhesion
molecules blocks leukocyte recruitment and thus tissue inflammation. The function of …

Pharmacological potential of tocotrienols: a review

H Ahsan, A Ahad, J Iqbal, WA Siddiqui - Nutrition & metabolism, 2014 - Springer
Tocotrienols, members of the vitamin E family, are natural compounds found in a number of
vegetable oils, wheat germ, barley, and certain types of nuts and grains. Like tocopherols …

Vitamin E: How much is enough, too much and why!

MG Traber, B Head - Free Radical Biology and Medicine, 2021 - Elsevier
Abstract α-Tocopherol (α-T) is a required dietary nutrient for humans and thus is a vitamin.
This narrative review focuses on vitamin E structures, functions, biological determinants and …

Vitamin E function and requirements in relation to PUFA

D Raederstorff, A Wyss, PC Calder, P Weber… - British Journal of …, 2015 - cambridge.org
Vitamin E (α-tocopherol) is recognised as a key essential lipophilic antioxidant in humans
protecting lipoproteins, PUFA, cellular and intra-cellular membranes from damage. The aim …

A history of vitamin E

E Niki, MG Traber - Annals of Nutrition and Metabolism, 2012 - karger.com
Vitamin E (α-tocopherol) was discovered nearly 100 years ago because it was required to
prevent fetal resorption in pregnant, vitamin E-deficient rats fed lard-containing diets that …

Vitamin E research: Past, now and future

R Brigelius-Flohé - Free Radical Biology and Medicine, 2021 - Elsevier
The early history of vitamin E from its discovery by Herbert M. Evans and Katharine JS
Bishop in 1922 up to its chemical synthesis by Paul Karrer and coworkers in 1938 and the …

Oxidative stress and cardiovascular disease: novel tools give (free) radical insight

IM Fearon, SP Faux - Journal of molecular and cellular cardiology, 2009 - Elsevier
Cardiovascular disease is the most common cause of mortality in the Western world and
accounts for up to a third of all deaths worldwide. Cardiovascular disease is multifactorial …