Multifunctional role of S100 protein family in the immune system: An update

P Singh, SA Ali - Cells, 2022 - mdpi.com
S100 is a broad subfamily of low-molecular weight calcium-binding proteins (9–14 kDa) with
structural similarity and functional discrepancy. It is required for inflammation and cellular …

[HTML][HTML] Topical nanocarriers for management of Rheumatoid Arthritis: A review

C Anita, M Munira, Q Mural, L Shaily - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Rheumatoid arthritis (RA) is a systemic autoimmune disease manifested by chronic joint
inflammation leading to severe disability and premature mortality. With a global prevalence …

Punicalagin ameliorates collagen-induced arthritis by downregulating M1 macrophage and pyroptosis via NF-κB signaling pathway

G Ge, J Bai, Q Wang, X Liang, H Tao, H Chen… - Science China Life …, 2022 - Springer
Rheumatoid arthritis (RA) is a chronic inflammatory disease that eventually leads to
disability. Inflammatory cell infiltration, severe joint breaking and systemic bone loss are the …

[PDF][PDF] JAK/STAT pathway and nociceptive cytokine signalling in rheumatoid arthritis and psoriatic arthritis

N Crispino, F Ciccia - Clin Exp Rheumatol, 2021 - clinexprheumatol.org
The key role of pro-inflammatory cytokines in the pathogenesis of rheumatoid arthritis (RA)
and psoriatic arthritis (PsA) is strongly supported by the observation that their blockage is …

From hurdle to springboard: The macrophage as target in biomaterial-based bone regeneration strategies

YH Kim, ROC Oreffo, JI Dawson - Bone, 2022 - Elsevier
The past decade has seen a growing appreciation for the role of the innate immune
response in mediating repair and biomaterial directed tissue regeneration. The long-held …

Emerging trends in microneedle-based drug delivery strategies for the treatment of rheumatoid arthritis

S Gorantla, U Batra, RN Samshritha… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction The current drug therapies for treating rheumatoid arthritis (RA) include
nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic drugs, or biological …

Targeted drug-delivery systems in the treatment of rheumatoid arthritis: recent advancement and clinical status

S Gorantla, G Singhvi, VK Rapalli, T Waghule… - Therapeutic …, 2020 - Future Science
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that is characterized by
synovial inflammation, cellular infiltration in joints which leads to progressive joint …

Traditional and modern management strategies for rheumatoid arthritis

M Akram, M Daniyal, S Sultana, A Owais, N Akhtar… - Clinica Chimica …, 2021 - Elsevier
Rheumatoid arthritis (RA) is a serious disorder of the joints affecting 1 or 2% of the
population aged between 20 and 50 years worldwide. RA is the foremost cause of disability …

Toxic effects of endocrine disruptor exposure on collagen-induced arthritis

R D'Amico, E Gugliandolo, M Cordaro, R Fusco… - Biomolecules, 2022 - mdpi.com
Endocrine disruptors (EDs) are chemical substances capable of affecting endocrine system
functioning and interfering with organ morphogenesis and physiological functions. The …

Adenosine deaminase modulates metabolic remodeling and orchestrates joint destruction in rheumatoid arthritis

SKS Bhagavatham, P Khanchandani, V Kannan… - Scientific Reports, 2021 - nature.com
Rheumatoid Arthritis (RA) is a chronic autoimmune disease associated with inflammation
and joint remodeling. Adenosine deaminase (ADA), a risk factor in RA, degrades adenosine …