Emerging trends in microneedle-based drug delivery strategies for the treatment of rheumatoid arthritis
S Gorantla, U Batra, RN Samshritha… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction The current drug therapies for treating rheumatoid arthritis (RA) include
nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic drugs, or biological …
nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic drugs, or biological …
Exploring the mechanism of Celastrol in the treatment of rheumatoid arthritis based on systems pharmacology and multi-omics
L Zeng, G Yu, K Yang, Q He, W Hao, W Xiang… - Scientific Reports, 2024 - nature.com
To explore the molecular network mechanism of Celastrol in the treatment of rheumatoid
arthritis (RA) based on a novel strategy (integrated systems pharmacology, proteomics …
arthritis (RA) based on a novel strategy (integrated systems pharmacology, proteomics …
RelA/MicroRNA-30a/NLRP3 signal axis is involved in rheumatoid arthritis via regulating NLRP3 inflammasome in macrophages
Q Yang, W Zhao, Y Chen, Y Chen, J Shi, R Qin… - Cell death & …, 2021 - nature.com
NLRP3 inflammasome plays an important role in the pathogenesis of rheumatoid arthritis
(RA). However, the post-transcriptional regulation of NLRP3 expression by miRNA in …
(RA). However, the post-transcriptional regulation of NLRP3 expression by miRNA in …
Chemical Characterization of Flowers and Leaf Extracts Obtained from Turnera subulata and Their Immunomodulatory Effect on LPS-Activated RAW 264.7 …
JRD Luz, EA Barbosa, TES Nascimento, AA Rezende… - Molecules, 2022 - mdpi.com
The anti-inflammatory properties of Turnera subulata have been evaluated as an alternative
drug approach to treating several inflammatory processes. Accordingly, in this study …
drug approach to treating several inflammatory processes. Accordingly, in this study …
Ononin induces cell apoptosis and reduces inflammation in rheumatoid arthritis fibroblast-like synoviocytes by alleviating MAPK and NF-κB signaling pathways
Y Meng, J Ji, X Xiao, M Li, S Niu, Y He… - Acta Biochimica …, 2021 - abp.ptbioch.edu.pl
As a kind of chronic inflammatory diseases, Rheumatoid arthritis (RA) has a low cure rate
and easy recurrence. It has widely reported that abnormal activation of mitogen-activated …
and easy recurrence. It has widely reported that abnormal activation of mitogen-activated …
Toxic effects of endocrine disruptor exposure on collagen-induced arthritis
Endocrine disruptors (EDs) are chemical substances capable of affecting endocrine system
functioning and interfering with organ morphogenesis and physiological functions. The …
functioning and interfering with organ morphogenesis and physiological functions. The …
Aceclofenac and methotrexate combination therapy could influence Th1/Th17 axis to modulate rheumatoid-arthritis-induced inflammation
Rheumatoid arthritis (RA) is an inflammatory, autoimmune and connective-tissue
arthropathy. The methotrexate (MTX) and aceclofenac (ACL) combination drug regimen is …
arthropathy. The methotrexate (MTX) and aceclofenac (ACL) combination drug regimen is …
Upregulating miR‑27a‑3p inhibits cell proliferation and inflammation of rheumatoid arthritis synovial fibroblasts through targeting toll‑like receptor 5
L Chen, Q Lu, J Chen, R Feng… - Experimental and …, 2021 - spandidos-publications.com
Rheumatoid arthritis (RA) is a serious chronic inflammatory disease and synovial fibroblasts
(SFs) serve a vital role in the pathogenesis and progression of RA. Current studies have …
(SFs) serve a vital role in the pathogenesis and progression of RA. Current studies have …
Revisiting p38 Mitogen-Activated Protein Kinases (MAPK) in inflammatory arthritis: a narrative of the emergence of MAPK-Activated Protein kinase inhibitors (MK2i)
The p38 mitogen-activated protein kinase (p38-MAPK) is a crucial signaling pathway closely
involved in several physiological and cellular functions, including cell cycle, apoptosis, gene …
involved in several physiological and cellular functions, including cell cycle, apoptosis, gene …
A large-scale Boolean model of the rheumatoid arthritis fibroblast-like synoviocytes predicts drug synergies in the arthritic joint
Rheumatoid arthritis (RA) is a complex autoimmune disease with an unknown aetiology.
However, rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS) play a significant role in …
However, rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS) play a significant role in …