Growing evidence indicates that synovial hypoxia-inducible factor 1α (HIF-1α) can be as a
promising target for RA therapy. We previously reported that AMSP-30 m as a novel HIF-1α …

Purpose Methotrexate (MTX) is an antineoplastic drug used in the treatment of rheumatoid
arthritis (RA). Given that it is a class IV drug with low permeability and solubility, this study …

Aim of the study The aim of this study was to test the anti-rheumatic arthritis effects of
Rhododendron molle G. Don leaf extract in arthritis rats and inflammatory RAW 264.7 cells …

Excessive production of pro-inflammatory cytokines such as interleukin (IL)-1β plays an
important role in the chronic inflammation in fibroblast-like synoviocytes (FLS) in rheumatoid …

Upadacitinib plasma concentrations, efficacy, and safety data from 216 subjects with
moderate‐to‐severe active Crohn's disease (CD) from the 16‐week induction period of the …

C-reactive protein (CRP) is an inflammatory biomarker with associated clinical utility in a
wide number of inflammatory disorders, including rheumatoid arthritis (RA). The interaction …

Abstract Objective The benefit of Se supplementation in rheumatoid arthritis (RA) has been
tested in clinical trials, but results remain inconclusive. The objective of this study was to …

As a traditional Chinese medicine, Rhododendron molle G. Don has a long history of
treating rheumatoid arthritis. In this study, RAW 264.7 cells induced by lipopolysaccharide …

Rheumatoid arthritis is a chronic autoimmune disease characterized by the infiltration of
synovial inflammatory cells and progressive joint destruction. Total flavonoids of Bidens …

Background: Lawsone (2-hydroxy-1, 4-naphthoquinone) is naturally present in Lawsonia
Inermis and flowers of Eicchornia crassipes. This study assessed the anti-arthritic potential …