Objective Pseudomonas aeruginosa is an opportunistic pathogen that infects the lungs of
people with cystic fibrosis (CF) and is the most common cause of chronic respiratory …

Antimicrobial resistance (AMR) has become a global medical priority that needs urgent
resolution. Pseudomonas aeruginosa is a versatile, adaptable bacterial species with …

The opportunistic pathogen Pseudomonas aeruginosa chronically infects the lungs of
patients with cystic fibrosis (CF). During infection the bacteria evolve and adapt to the lung …

Antimicrobial susceptibility testing (AST) remains the cornerstone of effective antimicrobial
selection and optimization in patients. Despite recent advances in rapid pathogen …

Management of the limited number of antimicrobials currently available requires the
identification of infections that contain drug-resistant isolates and the discovery of factors that …

Antimicrobial therapy is facing a worrisome and underappreciated challenge, the
phenomenon of heteroresistance (HR). HR has been gradually documented in clinically …

Bacteriocins are proteinaceous antimicrobials produced by bacteria that are active against
other strains of the same species. R-type pyocins are phage tail-like bacteriocins produced …

Most patients with an acute bacterial infection have immune defense mechanisms to
respond to the pathogen and destroy both resistant and non-resistant bacterial cells …

Objectives Cystic fibrosis (CF) patients are often colonized with Pseudomonas aeruginosa.
During treatment, P. aeruginosa can develop subpopulations exhibiting variable in vitro …

Background Pseudomonas aeruginosa is responsible for up to 10% of healthcare
associated urinary tract infections (UTI), which can be difficult to treat and can lead to …