Over the past millennia, life expectancy has drastically increased. While a mere 25 years
during Bronze and Iron ages, life expectancy in many European countries and in Japan is …

The blood–brain barrier (BBB) is the interface between the central nervous system and
systemic circulation. It tightly regulates what enters and is removed from the brain …

There is an ongoing need for accurate prognostic biomarkers in the milieu of acute ischemic
stroke (AIS) receiving reperfusion therapy. Neutrophil–lymphocyte ratio (NLR) has been …

The responses of central nervous system (CNS) cells such as neurons and glia in
neurodegenerative diseases (NDs) suggest that regulation of neuronal and glial functions …

Stroke is a severe and life-threatening disease, necessitating more research on new
treatment strategies. Infiltrated T lymphocytes, an essential adaptive immune cell with …

In recent decades there has been a large focus on understanding the mechanisms of
peripheral immune cell infiltration into the central nervous system (CNS) in …

Background The modulation of neuroinflammation is a new direction that may alleviate the
early brain injury after subarachnoid hemorrhage (SAH). Brain resident microglia …

Despite recent therapeutic advances, ischemic stroke is still a leading cause of death and
disability. There is renewed attention on peripheral inflammatory signaling as a way of …

Stroke is a very common disease being the leading cause of death and disability worldwide.
The immune response subsequent to an ischemic stroke is a crucial factor in its …

The aging of the global population poses significant scientific challenges. Moreover, the
biological process of aging is the most significant risk factor for most chronic illnesses; …