The role of FOLFIRINOX in metastatic pancreatic cancer: A meta-analysis
B Zhang, F Zhou, J Hong, DM Ng, T Yang… - World Journal of …, 2021 - Springer
Background The prognosis of pancreatic cancer (PC) is extremely poor, and most patients
with metastatic PC still receive palliative care. Here, we report the efficacy and safety of …
with metastatic PC still receive palliative care. Here, we report the efficacy and safety of …
[HTML][HTML] Tumor microenvironment in pancreatic ductal adenocarcinoma: Implications in immunotherapy
Pancreatic ductal adenocarcinoma is one of the most aggressive and lethal cancers.
Surgical resection is the only curable treatment option, but it is available for only a small …
Surgical resection is the only curable treatment option, but it is available for only a small …
Targeting Mutant KRAS in Pancreatic Cancer: Futile or Promising?
FI Nollmann, DA Ruess - Biomedicines, 2020 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal cancers with a dismal
prognosis for the patient. This is due to limited diagnostic options for the early detection of …
prognosis for the patient. This is due to limited diagnostic options for the early detection of …
CD44-targeting hydrophobic phosphorylated gemcitabine prodrug nanotherapeutics augment lung cancer therapy
Gemcitabine (GEM) is among the most used chemotherapies for advanced malignancies
including non-small cell lung cancer. The clinical efficacy of GEM is, however, downplayed …
including non-small cell lung cancer. The clinical efficacy of GEM is, however, downplayed …
Lucidone inhibits autophagy and MDR1 via HMGB1/RAGE/PI3K/Akt signaling pathway in pancreatic cancer cells
SY Chen, YH Hsu, SY Wang, YY Chen… - Phytotherapy …, 2022 - Wiley Online Library
Gemcitabine (GEM) drug resistance remains a difficult challenge in pancreatic ductal
adenocarcinoma (PDAC) treatment. Therefore, identifying a safe and effective treatment …
adenocarcinoma (PDAC) treatment. Therefore, identifying a safe and effective treatment …
Enhancing cancer chemo‐immunotherapy: innovative approaches for overcoming immunosuppression by functional nanomaterials
Chemotherapy is a critical modality in cancer therapy to combat malignant cell proliferation
by directly attacking cancer cells and inducing immunogenic cell death, serving as a vital …
by directly attacking cancer cells and inducing immunogenic cell death, serving as a vital …
Hexosamine pathway inhibition overcomes pancreatic cancer resistance to gemcitabine through unfolded protein response and EGFR-Akt pathway modulation
F Ricciardiello, Y Gang, R Palorini, Q Li, M Giampà… - Oncogene, 2020 - nature.com
Different evidence has indicated metabolic rewiring as a necessity for pancreatic cancer
(PC) growth, invasion, and chemotherapy resistance. A relevant role has been assigned to …
(PC) growth, invasion, and chemotherapy resistance. A relevant role has been assigned to …
Long non-coding RNAs in pancreatic cancer: biologic functions, mechanisms, and clinical significance
J Li, S Hou, Z Ye, W Wang, X Hu, Q Hang - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic cancer (PC) is a highly aggressive malignant tumor with a high
mortality rate. Growing evidence shows that long non-coding RNAs (lncRNAs) might …
mortality rate. Growing evidence shows that long non-coding RNAs (lncRNAs) might …
[HTML][HTML] Noncoding RNAs in drug-resistant pancreatic cancer: A review
Z Lin, S Lu, X Xie, X Yi, H Huang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Pancreatic cancer is the fourth-leading cause of cancer-related deaths and is expected to be
the second-leading cause of cancer-related deaths in Europe and the United States by …
the second-leading cause of cancer-related deaths in Europe and the United States by …
Exosomal ACADM sensitizes gemcitabine-resistance through modulating fatty acid metabolism and ferroptosis in pancreatic cancer
Y Yang, H Gu, K Zhang, Z Guo, X Wang, Q Wei… - BMC cancer, 2023 - Springer
This study aimed to evaluate the potential of exosomes from cancer cells to predict
chemoresistance in pancreatic cancer (PC) and explore the molecular mechanisms through …
chemoresistance in pancreatic cancer (PC) and explore the molecular mechanisms through …