Quinoline, which consists of benzene fused with N-heterocyclic pyridine, has received
considerable attention as a core template in drug design because of its broad spectrum of …

The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

The chemistry of nitrogen-containing heterocyclic compound pyrrole and pyrrolidine has
been a versatile field of study for a long time for its diverse biological and medicinal …

Dengue is one of the most typical viral infection categorized in the Neglected Tropical
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …

Cancer is a neoplastic disease that remains a global challenge with a reported prevalence
that is increasing annually. Though existing drugs can be applied as single or combined …

A new chitosan Schiff base was developed via the reaction of chitosan (CH) with 2-chloro-3-
formyl-7-ethoxy quinoline (Q) derivative. The alteration in the chemical structure and …

Two new classes of hybrid quinoline–imidazole/benzimidazole derivatives (the hybrid QIBS
salts and QIBC cycloadducts) were designed and synthesized to evaluate their anticancer …

Malaria is the fifth most lethal parasitic infection in the world. Antimalarial medications have
played a crucial role in preventing and eradicating malaria. Numerous heterocyclic moieties …

Tuberculosis, a disease of poverty is a communicable infection with a reasonably high
mortality rate worldwide. 10 Million new cases of TB were reported with approx 1.4 million …

Indoles are amongst the most essential class of heteroaromatics in organic chemistry, being
commonly found in biologically active natural products. Indole and its derivatives have …