A large number of studies have evidenced that developmental neurotoxicity induced by lead
(Pb) is related to oxidative injury. Furthermore, recent studies have found that developmental …

The developmental origin of health and disease hypothesis states that adverse fetal and
early childhood exposures can predispose to obesity, cardiovascular, and …

Reactive oxygen species (ROS) are essentially harmful for living organisms, including
human beings. It is well known that ROS-induced damage of cellular components may lead …

Exposure to the environmental pollutant lead (Pb) has been linked to Alzheimer's disease
(AD), in which mitochondrial dysfunction is a pathological consequence of neuronal …

Lead has been linked to the development of hypertension via oxidative stress. Catalase
plays an important role in the disposal of hydrogen peroxide in erythrocyte and its activity …

Stress has been described as a risk factor for the development of Alzheimer´ s disease (AD).
In the present work we aim to study the validity of an experimental model of neonatal chronic …

In recent years, the clinical importance of herbal drugs has received considerable attention
in reducing free radical‐induced tissue injury. Oxidative stress has been proposed as a …

OBJECTIVE: The objective was to study the efficacy of oral supplementation of gossypin, a
flavonoid, during lead exposure in preventive alterations in the heme synthesis pathway …

Alzheimer's Disease (AD) is a progressive, irreversible neurodegenerative disease. Despite
several genetic mutations (Haass et al., J. Biol. Chem. 269: 17741–17748, 1994; Ancolio et …

High metabolic activity and low levels of antioxidant enzymes make neurons particularly
prone to damage by reactive oxygen species. Thus, repair of oxidative DNA damage is …