ER-phagy: mechanisms, regulation, and diseases connected to the lysosomal clearance of the endoplasmic reticulum
F Reggiori, M Molinari - Physiological reviews, 2022 - journals.physiology.org
ER-phagy (reticulophagy) defines the degradation of portions of the endoplasmic reticulum
(ER) within lysosomes or vacuoles. It is part of the self-digestion (ie, autophagic) programs …
(ER) within lysosomes or vacuoles. It is part of the self-digestion (ie, autophagic) programs …
Autophagy and organelle homeostasis in cancer
DR Miller, A Thorburn - Developmental cell, 2021 - cell.com
Beginning with the earliest studies of autophagy in cancer, there have been indications that
autophagy can both promote and inhibit cancer growth and progression; autophagy …
autophagy can both promote and inhibit cancer growth and progression; autophagy …
ER‐phagy: shaping up and destressing the endoplasmic reticulum
S Wilkinson - The FEBS journal, 2019 - Wiley Online Library
The endoplasmic reticulum (ER) network has central roles in metabolism and cellular
organization. The ER undergoes dynamic alterations in morphology, molecular composition …
organization. The ER undergoes dynamic alterations in morphology, molecular composition …
ER-Phagy: a new regulator of ER homeostasis
M Yang, S Luo, X Wang, C Li, J Yang, X Zhu… - Frontiers in cell and …, 2021 - frontiersin.org
The endoplasmic reticulum (ER) is one of the most important cellular organelles and is
essential for cell homeostasis. Upon external stimulation, ER stress induces the unfolded …
essential for cell homeostasis. Upon external stimulation, ER stress induces the unfolded …
[HTML][HTML] Emerging principles of selective ER autophagy
S Wilkinson - Journal of molecular biology, 2020 - Elsevier
The endoplasmic reticulum (ER) is a fundamental organelle in cellular metabolism and
signal transduction. It is subject to complex, dynamic sculpting of morphology and …
signal transduction. It is subject to complex, dynamic sculpting of morphology and …
O-GlcNAc transferase regulates intervertebral disc degeneration by targeting FAM134B-mediated ER-phagy
R Luo, G Li, W Zhang, H Liang, S Lu… - … & Molecular Medicine, 2022 - nature.com
Both O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) and endoplasmic reticulum-
phagy (ER-phagy) are well-characterized conserved adaptive regulatory mechanisms that …
phagy (ER-phagy) are well-characterized conserved adaptive regulatory mechanisms that …
Endoplasmic reticulum stress signaling in cancer and neurodegenerative disorders: Tools and strategies to understand its complexity
DC da Silva, P Valentão, PB Andrade… - Pharmacological …, 2020 - Elsevier
The endoplasmic reticulum (ER) comprises a network of tubules and vesicles that
constitutes the largest organelle of the eukaryotic cell. Being the location where most …
constitutes the largest organelle of the eukaryotic cell. Being the location where most …
Excessive ER-phagy mediated by the autophagy receptor FAM134B results in ER stress, the unfolded protein response, and cell death in HeLa cells
Autophagy is typically a prosurvival cellular process that promotes the turnover of long-lived
proteins and damaged organelles, but it can also induce cell death. We have previously …
proteins and damaged organelles, but it can also induce cell death. We have previously …
Long-chain noncoding ribonucleic acids affect the survival and prognosis of patients with esophageal adenocarcinoma through the autophagy pathway: construction …
L Wu, Y Zheng, X Ruan, D Wu, P Xu, J Liu… - Anti-cancer …, 2022 - journals.lww.com
Autophagy-related long-chain noncoding ribonucleic acids play a vital role in the
development of esophageal adenocarcinoma. This study aimed to construct a prognostic …
development of esophageal adenocarcinoma. This study aimed to construct a prognostic …