Neuromodulation in epilepsy: state-of-the-art approved therapies
Three neuromodulation therapies have been appropriately tested and approved in refractory
focal epilepsies: vagus nerve stimulation (VNS), deep brain stimulation of the anterior …
focal epilepsies: vagus nerve stimulation (VNS), deep brain stimulation of the anterior …
Cycles in epilepsy
Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …
Long-term brain network reorganization predicts responsive neurostimulation outcomes for focal epilepsy
AN Khambhati, A Shafi, VR Rao… - Science Translational …, 2021 - science.org
Responsive neurostimulation (RNS) devices, able to detect imminent seizures and to rapidly
deliver electrical stimulation to the brain, are effective in reducing seizures in some patients …
deliver electrical stimulation to the brain, are effective in reducing seizures in some patients …
[HTML][HTML] Seizure diaries and forecasting with wearables: epilepsy monitoring outside the clinic
It is a major challenge in clinical epilepsy to diagnose and treat a disease characterized by
infrequent seizures based on patient or caregiver reports and limited duration clinical …
infrequent seizures based on patient or caregiver reports and limited duration clinical …
Seizure cycles in focal epilepsy
Importance Focal epilepsy is characterized by the cyclical recurrence of seizures, but, to our
knowledge, the prevalence and patterns of seizure cycles are unknown. Objective To …
knowledge, the prevalence and patterns of seizure cycles are unknown. Objective To …
Ambulatory seizure forecasting with a wrist-worn device using long-short term memory deep learning
The ability to forecast seizures minutes to hours in advance of an event has been verified
using invasive EEG devices, but has not been previously demonstrated using noninvasive …
using invasive EEG devices, but has not been previously demonstrated using noninvasive …
Multiday cycles of heart rate are associated with seizure likelihood: An observational cohort study
Background Circadian and multiday rhythms are found across many biological systems,
including cardiology, endocrinology, neurology, and immunology. In people with epilepsy …
including cardiology, endocrinology, neurology, and immunology. In people with epilepsy …
Seizure forecasting using a novel sub-scalp ultra-long term EEG monitoring system
Accurate identification of seizure activity, both clinical and subclinical, has important
implications in the management of epilepsy. Accurate recognition of seizure activity is …
implications in the management of epilepsy. Accurate recognition of seizure activity is …
Seizure occurrence is linked to multiday cycles in diverse physiological signals
Objective The factors that influence seizure timing are poorly understood, and seizure
unpredictability remains a major cause of disability. Work in chronobiology has shown that …
unpredictability remains a major cause of disability. Work in chronobiology has shown that …
Forecasting seizure likelihood with wearable technology
The unpredictability of epileptic seizures exposes people with epilepsy to potential physical
harm, restricts day-to-day activities, and impacts mental well-being. Accurate seizure …
harm, restricts day-to-day activities, and impacts mental well-being. Accurate seizure …