Naringenin is flavorless, water insoluble active principle belonging to flavanone subclass. It
exhibits a diverse pharmacological profile as well as divine nutraceutical values. Although …

As the advancements in the medical technology and healthcare develop through the years,
combinational therapy has evolved to be an important treatment modality in many disease …

The ambient humidity varies with seasons and geographical altitude across the regions. A
change in relative humidity during processing, storage, and transportation can cause …

Spherical crystallization is widely employed in pharmaceutical industry to produce spherical
particles that exhibit improved micrometric performances of active pharmaceutical …

The global pandemic caused by infections of the new coronavirus (COVID-19) makes it
necessary to find possible less toxic and easily accessible therapeutic agents. In this study …

Abstract Carbamazepine (CBZ), a Biopharmaceutics Classification System (BCS) class II
drug, is widely-used as a first line antiepileptic drug. Numbers of cocrystals have reported to …

Apigenin (4′, 5, 7-trihydroxyflavone, APG) has many potential therapeutic benefits;
however, its poor aqueous solubility has limited its clinical applications. In this work, a large …

Palbociclib (PAL) is an effective anti-breast cancer drug, but its use has been partly
restricted due to poor bioavailability (resulting from extremely low water solubility) and …

Many heterocycles have been developed as drugs due to their capacity to interact
productively with biological systems. The present study aimed to synthesize cocrystals of the …

Dexamethasone (DEX), a widely prescribed anti-inflammatory drug, displays limited crystal
forms. Cocrystallization constitutes an untapped strategy for expanding its solid-state …