Possible mechanisms of oxidative stress-induced skin cellular senescence, inflammation, and cancer and the therapeutic potential of plant polyphenols

HM Liu, MY Cheng, MH Xun, ZW Zhao… - International Journal of …, 2023 - mdpi.com
As the greatest defense organ of the body, the skin is exposed to endogenous and external
stressors that produce reactive oxygen species (ROS). When the antioxidant system of the …

Exogenous drugs-induced mouse models of atopic dermatitis

R Zheng, Y Ren, X Liu, C He, H Liu, Y Wang, J Li… - Cytokine & Growth …, 2024 - Elsevier
Atopic dermatitis (AD) is an inflammatory skin disease characterized by intense pruritus. AD
is harmful to both children and adults, but its pathogenic mechanism has yet to be fully …

[HTML][HTML] Epigenetic control of inflammation in Atopic Dermatitis

S Akhtar, RKME Alsayed, F Ahmad… - Seminars in Cell & …, 2024 - Elsevier
Atopic dermatitis (AD), also known as atopic eczema, is a common but also complex chronic,
itchy skin condition with underlying inflammation of the skin. This skin ailment is prevalent …

In vitro and in vivo exploration of the anti-atopic dermatitis mechanism of action of Tibetan medicine Qi-Sai-Er-Sang-Dang-Song decoction

J Liu, Y Tao, X Zou, Q Liu, X Meng, Y Zhang… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Tibetan medicine Qi-Sai-Er-Sang-Dang-Song
Decoction (QSD, ཆུ་ སེར་ སེང་ ལྡེང་ སུམ་ ཐང་།) is a traditional Tibetan medical …

Based on network pharmacology, molecular docking and experimental verification to reveal the mechanism of andrographis paniculata against solar dermatitis.

Q Deng, W Chen, B Deng, W Chen, L Chen, G Fan… - Phytomedicine, 2024 - Elsevier
Background Solar dermatitis (SD) is an acute, damaging inflammation of the skin caused by
UV exposure, especially UVB. Therefore, the discovery of novel anti-SD therapeutic agents …

[HTML][HTML] Anti-atopic dermatitis effect of fraxinellone via inhibiting IL-31 in vivo and in vitro

N Yang, J Deng, H Xu, H Dai, H Jin, H Shao, Y Liu - Heliyon, 2024 - cell.com
Chronic recurrent itch and skin inflammation are prominent features of atopic dermatitis
(AD), which is closely related to the immune response driven by T-helper type 2 (Th2) cells …

Anti-Atopic Effect of Scutellaria baicalensis and Raphanus sativus on Atopic Dermatitis-like Lesions in Mice by Experimental Verification and Compound-Target …

J Lee, YS Seo, AY Lee, HH Nam, KY Ji, T Kim, S Lee… - Pharmaceuticals, 2024 - mdpi.com
Scutellaria baicalensis Georgi and Raphanus Sativus Linne herbal mixture (SRE) is a
Chinese herbal medicine. In this study, we aimed to evaluate the therapeutic efficacy of SRE …

[HTML][HTML] Perspective Chapter: Integrated Network Pharmacology and Multiomics Approach to Elucidate the Repositioning of Fatal Food Toxins to Lifesaving Anticancer …

FA Badria, M Foda - 2023 - intechopen.com
This research investigates repurposing potato glycoalkaloids as lifesaving anticancer drugs.
There is integration of network pharmacology with multiomics. Solanine, chaconine, and …

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation

H Shao, J Deng, Y Liu, N Yang - JoVE (Journal of Visualized Experiments), 2023 - jove.com
Skin is the human body's first line of defense and one of the most exposed organs to
environmental chemicals. Allergic contact dermatitis (ACD) is a common skin disease that …

Unveiling the antiviral mechanism of Forsythia suspensa: A comprehensive analysis of screening targets and components.

N Sun, S Ma, L Jin, X Zhang, M Zhou… - Journal of Chinese …, 2024 - search.ebscohost.com
Forsythia suspensa, a traditional Chinese medicine, exhibits notable antiviral effects,
particularly in the context of treating COVID-19. Despite its efficacy, the specific antiviral …