More than 30 heritable conditions are associated with thoracic aortic aneurysm and
dissection (TAAD). Heritable syndromic conditions, such as Marfan syndrome, Loeys-Dietz …

Background Marfan syndrome is associated with morbidity and mortality due to aortic
dilatation and dissection. Preventive aortic root replacement has been the standard …

OBJECTIVES Root reimplantation has been the favoured approach for patients with
heritable aortic disorder requiring valve-sparring root replacement. In the past few years …

Objectives To assess intermediate-term outcomes of aortic root replacement with valve-
sparing reimplantation of bicuspid aortic valves (BAV), compared with tricuspid aortic valves …

Marfan syndrome (MFS) is an autosomal dominant heritable disorder of connective tissue
that affects the cardiovascular, skeletal, ocular, pulmonary, and nervous systems and is …

Background The usefulness of aortic valve sparing operations to treat aortic root aneurysm
in patients with Marfan syndrome (MS) remains controversial. Objectives The purpose of this …

Objective The objective of this study was to compare midterm outcomes of aortic valve-
replacing root replacement (AVR) and aortic valve-sparing root replacement (AVS) …

Over the past 4 decades, remarkable progress in understanding the cause, pathogenesis,
and management of the MFS has led to an increase in life expectancy to near normal for …

Background: Personalized external aortic root support (PEARS) was introduced in 2004 for
prevention of aortic root dilatation in Marfan patients. The individual's aortic root is replicated …

Background Valve-sparing root replacement (VSRR) has excellent outcomes when
performed in experienced centers in well-selected patients. It is suggested that …