Background Marfan syndrome (MFS) is a disorder of autosomal dominant inheritance, in
which aortic root dilation is the main cause of morbidity and mortality. Fibrillin-1 (FBN-1) …

Background and objectives In personalised external aortic root support (PEARS), a custom-
made, macroporous mesh is used to stabilise a dilated aortic root and prevent dissection …

Background We present our results after elective, isolated David I procedures over the past
20 years. Methods Between 1993 and 2015, 197 patients (mean age 46±17 years, 73 …

OBJECTIVES Valve-sparing aortic root replacement (VSARR) is recommended for patients
with aortic root dilatation and preserved aortic valve cusp morphology. The durability of …

The objective of this study is to understand the formation of vortices and other flow
characteristics associated with the three-dimensional motions of an incompressible Navier …

Marfan syndrome (MFS) is an autosomal dominant genetic disorder caused by mutations in
the fibrillin-1 gene. Acute aortic dissection is the leading cause of death in patients suffering …

Objective The lack of annular stabilization is the drawback of aortic root remodeling, and
recently the addition of annuloplasty has been proposed. Limited data, however, exist on …

Background In patients with a bicuspid aortic valve presenting with aortic insufficiency (AI)
and root aneurysm, we assessed whether outcomes with primary cusp repair with root …

Reimplantation of the aortic valve has been performed for 3 decades, and experience shows
that patient selection and meticulous operative technique are crucial to provide excellent …

Objectives Aortic root replacement using a composite graft is the treatment of choice for a
large variety of aortic root conditions with a diseased aortic valve. The objective of the …