Antimicrobial resistance is an old and silent pandemic. Resistant organisms emerge in
parallel with new antibiotics, leading to a major global public health crisis over time …

Antimicrobial resistance (AMR) is one of the most important global public health problems.
The imprudent use of antibiotics in humans and animals has resulted in the emergence of …

Infection of multidrug-resistant (MDR) bacteria, such as methicillin-resistant Staphylococcus
aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), and extended-spectrum …

Pseudomonas aeruginosa can utilize various virulence factors necessary for host infection
and persistence. These virulence factors include pyocyanin, proteases, exotoxins, 2-heptyl-4 …

The number of multidrug-resistant bacteria is rapidly spreading worldwide. Among the
various mechanisms determining resistance to antimicrobial agents, multidrug efflux pumps …

Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …

Antibiotic efflux is a mechanism that is well-documented in the phenotype of multidrug
resistance in bacteria. Efflux is considered as an early facilitating mechanism in the bacterial …

Pseudomonas aeruginosa is a ubiquitous Gram-negative bacterium renowned for its
resilience and adaptability across diverse environments, including clinical settings, where it …

Background Increased expression of efflux pumps is an important mechanism of antibiotic
resistance in Pseudomonas aeruginosa, and treatment with inhibitors of active efflux pumps …

Sepsis is a life-threatening condition and a significant cause of preventable morbidity and
mortality globally. Among the leading causative agents of sepsis are bacterial pathogens …