Current understanding of the pathogenesis of dengue virus infection

P Bhatt, SP Sabeena, M Varma, G Arunkumar - Current microbiology, 2021 - Springer
The pathogenesis of dengue virus infection is attributed to complex interplay between virus,
host genes and host immune response. Host factors such as antibody-dependent …

Risk and predictive factors for severe dengue infection: A systematic review and meta-analysis

K Yuan, Y Chen, M Zhong, Y Lin, L Liu - PLoS One, 2022 - journals.plos.org
Background Dengue is a major public health issue worldwide and severe dengue (SD) is
life threatening. It is critical to triage patients with dengue infection in the early stage …

[HTML][HTML] Epidemiology and costs of dengue in Brazil: a systematic literature review

JBS Junior, E Massad, A Lobao-Neto, R Kastner… - International Journal of …, 2022 - Elsevier
Objectives Dengue infection is a growing public health problem, with the number of reported
cases increasing in the Americas and worldwide. This review characterized the …

Dengue prediction in Latin America using machine learning and the one health perspective: a literature review

M Cabrera, J Leake, J Naranjo-Torres… - Tropical Medicine and …, 2022 - mdpi.com
Dengue fever is a serious and growing public health problem in Latin America and
elsewhere, intensified by climate change and human mobility. This paper reviews the …

Cholesterol-lowering drugs as potential antivirals: a repurposing approach against flavivirus infections

JF Osuna-Ramos, CN Farfan-Morales… - Viruses, 2023 - mdpi.com
Flaviviruses, including Dengue (DENV), Zika (ZIKV), and Yellow Fever (YFV) viruses,
represent a significant global health burden. The development of effective antiviral therapies …

Immune-mediated pathogenesis in dengue virus infection

A Khanam, H Gutiérrez-Barbosa, KE Lyke, JV Chua - Viruses, 2022 - mdpi.com
Dengue virus (DENV) infection is one of the major public health concerns around the globe,
especially in the tropical regions of the world that contribute to 75% percent of dengue …

Rapid, field-deployable nucleobase detection and identification using FnCas9

M Azhar, R Phutela, AH Ansari, D Sinha, N Sharma… - BioRxiv, 2020 - biorxiv.org
Detection of pathogenic sequences or variants in DNA and RNA through a point-of-care
diagnostic approach is valuable for rapid clinical prognosis. In recent times, CRISPR based …

Plasma leakage in dengue: a systematic review of prospective observational studies

C Rodrigo, C Sigera, D Fernando, S Rajapakse - BMC infectious diseases, 2021 - Springer
Plasma leakage is a precursor to life-threatening complications of dengue, but this group is
poorly defined and not often reported in literature. Patients with Dengue haemorrhagic fever …

Early transcriptomic host response signatures in the serum of dengue patients provides insights into clinical pathogenesis and disease severity

A Yadav, U Shamim, V Ravi, P Devi, P Kumari… - Scientific Reports, 2023 - nature.com
Dengue virus (DENV), known to cause viral infection, belongs to the family Flaviviridae,
having four serotypes (DENV1-4) that spreads by the bite of the Aedes aegypti mosquito …

Recent advances in natural products as potential inhibitors of dengue virus with a special emphasis on NS2b/NS3 protease

FG Saqallah, MA Abbas, HA Wahab - Phytochemistry, 2022 - Elsevier
Dengue virus (DENV) is an arbovirus widespread through tropical and subtropical areas. It
is transmitted to humans through Aedes mosquitoes. Infections with DENV can lead to a …