Status and prospects of genome‐wide association studies in plants

L Tibbs Cortes, Z Zhang, J Yu - The plant genome, 2021 - Wiley Online Library
Genome‐wide association studies (GWAS) have developed into a powerful and ubiquitous
tool for the investigation of complex traits. In large part, this was fueled by advances in …

[PDF][PDF] Genome-wide association study of complex traits in maize detects genomic regions and genes for increasing grain yield and grain quality

Y Dwiningsih, J Al-Kahtani - Advance Sustainable Science …, 2022 - academia.edu
This review describes the current status of genome-wide association study (GWAS) of the
major crops in maize (Zea mays L.) concentrate on performing association mapping as a …

GAPIT version 3: boosting power and accuracy for genomic association and prediction

J Wang, Z Zhang - Genomics, Proteomics and Bioinformatics, 2021 - academic.oup.com
Genome-wide association study (GWAS) and genomic prediction/selection (GP/GS) are the
two essential enterprises in genomic research. Due to the great magnitude and complexity …

[HTML][HTML] Iterative usage of fixed and random effect models for powerful and efficient genome-wide association studies

X Liu, M Huang, B Fan, ES Buckler, Z Zhang - PLoS genetics, 2016 - journals.plos.org
False positives in a Genome-Wide Association Study (GWAS) can be effectively controlled
by a fixed effect and random effect Mixed Linear Model (MLM) that incorporates population …

BLINK: a package for the next level of genome-wide association studies with both individuals and markers in the millions

M Huang, X Liu, Y Zhou, RM Summers, Z Zhang - Gigascience, 2019 - academic.oup.com
Big datasets, accumulated from biomedical and agronomic studies, provide the potential to
identify genes that control complex human diseases and agriculturally important traits …

Comprehensive evaluation of mapping complex traits in wheat using genome-wide association studies

DK Saini, Y Chopra, J Singh, KS Sandhu, A Kumar… - Molecular …, 2022 - Springer
Genome-wide association studies (GWAS) are effectively applied to detect the marker trait
associations (MTAs) using whole genome-wide variants for complex quantitative traits in …

[HTML][HTML] Genome-wide association studies in maize: praise and stargaze

Y Xiao, H Liu, L Wu, M Warburton, J Yan - Molecular plant, 2017 - cell.com
Genome-wide association study (GWAS) has become a widely accepted strategy for
decoding genotype-phenotype associations in many species thanks to advances in next …

[HTML][HTML] Comparing different statistical models and multiple testing corrections for association mapping in soybean and maize

AS Kaler, JD Gillman, T Beissinger… - Frontiers in plant …, 2020 - frontiersin.org
Association mapping (AM) is a powerful tool for fine mapping complex trait variation down to
nucleotide sequences by exploiting historical recombination events. A major problem in AM …

Methodological implementation of mixed linear models in multi-locus genome-wide association studies

YJ Wen, H Zhang, YL Ni, B Huang… - Briefings in …, 2018 - academic.oup.com
The mixed linear model has been widely used in genome-wide association studies (GWAS),
but its application to multi-locus GWAS analysis has not been explored and assessed. Here …

GAPIT version 2: an enhanced integrated tool for genomic association and prediction

Y Tang, X Liu, J Wang, M Li, Q Wang, F Tian… - The plant …, 2016 - Wiley Online Library
Most human diseases and agriculturally important traits are complex. Dissecting their
genetic architecture requires continued development of innovative and powerful statistical …