Abstract Development of resistance to chemotherapy in cancer continues to be a major
challenge in cancer management. Ferroptosis, a unique type of cell death, is mechanistically …

Iron-dependent lipid peroxidation causes ferroptosis, a form of regulated cell death. Crucial
steps in the formation of ferroptosis include the accumulation of ferrous ions (Fe2+) and lipid …

Ferroptosis is a mode of cell death regulated by iron-dependent lipid peroxidation. Growing
evidence suggests ferroptosis induction as a novel anti-cancer modality that could …

Induction of ferroptosis emerges as an effective method for cancer treatment. With massive
efforts to elucidate the ferroptosis mechanism, the development of new ferroptosis inducers …

Ferroptosis, an established form of programmed cell death discovered in 2012, is
characterized by an imbalance in iron metabolism, lipid metabolism, and antioxidant …

The brain tumor is a kind of malignant tumor with brutal treatment, high recurrence rate, and
poor prognosis, and the incidence and death rate is increasing yearly. Surgery is often used …

Leukemia circulates in the bloodstream and induces various symptoms and complications.
Occasionally, these cells accumulate in non‐marrow tissues, forming a tumor‐like myeloid …

Cancers polarized to a mesenchymal or poorly differentiated state can often evade cell
death induced by conventional therapies. The epithelial-mesenchymal transition is involved …

KIAA1429, an important component of the N6-methyladenine methyltransferase complex, is
involved in the pathology of many types of cancer. In this study, the mechanisms through …

Ferroptosis differs from traditional cell death mechanisms like apoptosis, necrosis, and
autophagy, primarily due to its reliance on iron metabolism and the loss of glutathione …