Tumor neurobiology and the war of nerves in cancer
S Faulkner, P Jobling, B March, CC Jiang… - Cancer discovery, 2019 - AACR
Nerves are emerging regulators of cancer progression. Cancer cells induce the outgrowth of
nerves in the tumor microenvironment through the release of neurotrophic factors, and in …
nerves in the tumor microenvironment through the release of neurotrophic factors, and in …
Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesis
Glioblastoma (GBM) is the most lethal primary adult brain tumor and its pathology is
hallmarked by distorted neovascularization, diffuse tumor-associated macrophage …
hallmarked by distorted neovascularization, diffuse tumor-associated macrophage …
Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 …
W Li, C Zhou, L Yu, Z Hou, H Liu, L Kong, Y Xu, J He… - Autophagy, 2024 - Taylor & Francis
Bevacizumab plays an important role in the first and second line treatment for metastatic
colorectal cancer (CRC). And induction of hypoxia and the tumors response to it plays an …
colorectal cancer (CRC). And induction of hypoxia and the tumors response to it plays an …
A class of extracellular vesicles from breast cancer cells activates VEGF receptors and tumour angiogenesis
Non-classical secretory vesicles, collectively referred to as extracellular vesicles (EVs), have
been implicated in different aspects of cancer cell survival and metastasis. Here, we …
been implicated in different aspects of cancer cell survival and metastasis. Here, we …
Therapeutic cancer vaccine and combinations with antiangiogenic therapies and immune checkpoint blockade
A Mougel, M Terme, C Tanchot - Frontiers in immunology, 2019 - frontiersin.org
Considering the high importance of immune surveillance and immune escape in the
evolution of cancer, the development of immunotherapeutic strategies has become a major …
evolution of cancer, the development of immunotherapeutic strategies has become a major …
LncRNA H19 promotes glioma angiogenesis through miR-138/HIF-1α/VEGF axis.
ZZ Liu, YF Tian, H Wu, SY Ouyang, WL Kuang - Neoplasma, 2020 - search.ebscohost.com
Glioma is one of the most common and aggressive malignant primary brain tumors with high
recurrence rate and mortality rate and heavily depends on the angiogenesis. LncRNA H19 …
recurrence rate and mortality rate and heavily depends on the angiogenesis. LncRNA H19 …
Electrospun nanofibers for drug delivery and biosensing
Early diagnosis and efficient treatment are of paramount importance to fighting cancers.
Monitoring the foreign body response of a patient to treatment therapies also plays an …
Monitoring the foreign body response of a patient to treatment therapies also plays an …
Apatinib for molecular targeted therapy in tumor
H Zhang - Drug design, development and therapy, 2015 - Taylor & Francis
As tumor angiogenesis is one of the hallmarks of cancer, the inhibition of vascular
endothelial growth factor signaling has become an attractive anticancer approach. Apatinib …
endothelial growth factor signaling has become an attractive anticancer approach. Apatinib …
Astrocytes, the rising stars of the glioblastoma microenvironment
M Brandao, T Simon, G Critchley, G Giamas - Glia, 2019 - Wiley Online Library
Glioblastoma (GBM) is an aggressive primary tumor, causing thousands of deaths
worldwide every year. The mean survival of patients with GBM remains below 20 months …
worldwide every year. The mean survival of patients with GBM remains below 20 months …
Exercise as adjunct therapy in cancer
Data from observational studies indicate that both physical activity as well as exercise (ie,
structured physical activity) is associated with reductions in the risk of recurrence and cancer …
structured physical activity) is associated with reductions in the risk of recurrence and cancer …