[HTML][HTML] Microbes, metabolites, and the gut–lung axis

AT Dang, BJ Marsland - Mucosal immunology, 2019 - Elsevier
The microbiota plays an essential role in the education, development, and function of the
immune system, both locally and systemically. Emerging experimental and epidemiological …

Macrophages: Their role, activation and polarization in pulmonary diseases

S Arora, K Dev, B Agarwal, P Das, MA Syed - Immunobiology, 2018 - Elsevier
Macrophages, circulating in the blood or concatenated into different organs and tissues
constitute the first barrier against any disease. They are foremost controllers of both innate …

Dietary fiber confers protection against flu by shaping Ly6c− patrolling monocyte hematopoiesis and CD8+ T cell metabolism

A Trompette, ES Gollwitzer, C Pattaroni… - Immunity, 2018 - cell.com
Dietary fiber protects against chronic inflammatory diseases by dampening immune
responses through short-chain fatty acids (SCFAs). Here we examined the effect of dietary …

The roles of macrophage polarization in the host immune response to sepsis

X Chen, Y Liu, Y Gao, S Shou, Y Chai - International immunopharmacology, 2021 - Elsevier
Sepsis is a life-threatening clinical syndrome caused by infection. Its pathogenesis is
complex and entails coagulation dysfunction, inflammation, and immune disorders …

Molecular mechanisms that influence the macrophage M1–M2 polarization balance

N Wang, H Liang, K Zen - Frontiers in immunology, 2014 - frontiersin.org
As an essential component of innate immunity, macrophages have multiple functions in both
inhibiting or promoting cell proliferation and tissue repair. Diversity and plasticity are …

From monocytes to M1/M2 macrophages: phenotypical vs. functional differentiation

P Italiani, D Boraschi - Frontiers in immunology, 2014 - frontiersin.org
Studies on monocyte and macrophage biology and differentiation have revealed the
pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue …

MiRNA-mediated macrophage polarization and its potential role in the regulation of inflammatory response

K Essandoh, Y Li, J Huo, GC Fan - Shock, 2016 - journals.lww.com
Monocytes and macrophages are important components of the immune system, specialized
in either removing pathogens as part of innate immunity or contributing to adaptive immunity …

Macrophage polarization in the development and progression of ovarian cancers: an overview

H Cheng, Z Wang, L Fu, T Xu - Frontiers in oncology, 2019 - frontiersin.org
Ovarian cancer is the most lethal gynecological malignancy worldwide. Most patients are
diagnosed at late stages because of atypical symptoms and the lack of effective early …

Novel H2S-Releasing hydrogel for wound repair via in situ polarization of M2 macrophages

J Wu, A Chen, Y Zhou, S Zheng, Y Yang, Y An, K Xu… - Biomaterials, 2019 - Elsevier
Abstract Hydrogen sulfide (H 2 S), as a gaseous messenger, exhibits potential therapeutic
effects in biological and clinical applications. Herein, an in situ forming biomimetic …

Chronic implant-related bone infections—can immune modulation be a therapeutic strategy?

E Seebach, KF Kubatzky - Frontiers in immunology, 2019 - frontiersin.org
Chronic implant-related bone infections are a major problem in orthopedic and trauma-
related surgery with severe consequences for the affected patients. As antibiotic resistance …