[HTML][HTML] Designer exosomes: a new platform for biotechnology therapeutics

D Jafari, S Shajari, R Jafari, N Mardi, H Gomari, F Ganji… - BioDrugs, 2020 - Springer
Desirable features of exosomes have made them a suitable manipulative platform for
biomedical applications, including targeted drug delivery, gene therapy, cancer diagnosis …

[HTML][HTML] Tetraspanins, more than markers of extracellular vesicles in reproduction

J Jankovičová, P Sečová, K Michalková… - International Journal of …, 2020 - mdpi.com
The participation of extracellular vesicles in many cellular processes, including reproduction,
is unquestionable. Although currently, the tetraspanin proteins found in extracellular vesicles …

Extracellular acidity and increased exosome release as key phenotypes of malignant tumors

M Logozzi, E Spugnini, D Mizzoni, R Di Raimo… - Cancer and Metastasis …, 2019 - Springer
The tumor milieu is characteristically acidic as a consequence of the fermentative
metabolism of glucose that results in massive accumulation of lactic acid within the …

Breakthroughs and new horizons in reproductive biology of rare and endangered animal species

P Comizzoli, WV Holt - Biology of Reproduction, 2019 - academic.oup.com
Because of higher extinction rates due to human and natural factors, more basic and applied
research in reproductive biology is required to preserve wild species and design proper …

[HTML][HTML] Oviductal extracellular vesicles interact with the spermatozoon's head and mid-piece and improves its motility and fertilizing ability in the domestic cat

MAMM Ferraz, A Carothers, R Dahal, MJ Noonan… - Scientific Reports, 2019 - nature.com
Fertilization and early embryo development are regulated by a unique maternal-
gamete/embryo cross-talk within the oviduct. Recent studies have shown that extracellular …

[HTML][HTML] Determining extracellular vesicles properties and miRNA cargo variability in bovine milk from healthy cows and cows undergoing subclinical mastitis

MD Saenz-de-Juano, G Silvestrelli, S Bauersachs… - BMC genomics, 2022 - Springer
Background Subclinical mastitis, the inflammation of the mammary gland lacking clinical
symptoms, is one of the most prevalent and costly diseases in dairy farming worldwide. Milk …

[HTML][HTML] Extracellular vesicles and the oviduct function

EA Harris, KK Stephens, W Winuthayanon - International Journal of …, 2020 - mdpi.com
In mammals, the oviduct (or the Fallopian tube in humans) can be divided into the
infundibulum (responsible for oocyte pick-up), ampulla (site of fertilization), isthmus (where …

Porcine oviductal extracellular vesicles interact with gametes and regulate sperm motility and survival

AS Alcântara-Neto, L Schmaltz, E Caldas, MC Blache… - Theriogenology, 2020 - Elsevier
Once in the female reproductive tract, spermatozoa undergo several modifications to acquire
their complete fertilizing ability. Interactions between the oviductal fluid (OF) and gametes …

[HTML][HTML] Roles of steroid hormones in oviductal function

BE Barton, GG Herrera, P Anamthathmakula… - …, 2020 - rep.bioscientifica.com
The oviduct (known as the fallopian tube in humans) is the site for fertilization and pre-
implantation embryo development. Female steroid hormones, estrogen and progesterone …

[HTML][HTML] The role of MicroRNAs in mammalian fertility: from gametogenesis to embryo implantation

D Salilew-Wondim, S Gebremedhn, M Hoelker… - International journal of …, 2020 - mdpi.com
The genetic codes inscribed during two key developmental processes, namely
gametogenesis and embryogenesis, are believed to determine subsequent development …